A survey on the prevalence of health care-associated infections at the Fann University Hospital in Dakar, Senegal.

Objectives: This study aimed to determine the prevalence of health care-associated infections (HAIs) at Fann Hospital, describe the profile of patients with HAI, and identify the causative pathogens.

Methods: This was a cross-sectional survey of the records of patients hospitalized in eight departments of the Fann University Hospital for a microbiologically confirmed HAI from January 1, 2024 to March 31, 2024. Data were collected using an HAI surveillance form and analyzed using R software version 4.

Tenofovir plasma concentrations related to estimated glomerular filtration rate changes in first-line regimens in African HIV-infected patients: ANRS 12115 DAYANA substudy.

Objectives: An open-label randomized trial (DAYANA) was conducted in sub-Saharan settings to evaluate four different regimens containing tenofovir disoproxil fumarate as first-line treatment for HIV infection. The objectives of the present substudy were to assess the relationship between trough concentrations of tenofovir in plasma collected after 24 h (C24) and estimated glomerular filtration rates (eGFR) calculated by the different formulae that are available.

Methods: The criteria for eligibility were those of the DAYANA trial, recruiting naive patients.