Correlation of marker periodontopathogenic bacteria with the immune component sCD secretion level in inflammatory periodontal diseases.

Lipopolysaccharide of the cell wall of gram-negative bacteria is a highly active biological substance: its interaction with toll-like receptors-4 (TLR-4) of myeloid cells leads to the activation of a cascade of inflammatory reactions, which is accompanied by the release of the soluble CD14 receptor (sCD14), which can be considered not only as a marker of cell activation by endotoxin, but also as a marker of microbial translocation. The aim of the work was to assess the prognostic significance of the sCD14 level in the samples of the periodontal pocket in inflammatory periodontal diseases and the relationship of its secretion with marker periodontopathogens. For the study, washes were obtained from the periodontal pocket (88 samples in total) from patients with chronic periodontitis and intact periodontium.

Spectrum and resistance determinants of oral streptococci clinical isolates.

The profiles of oral streptococci sensitivity to antibacterial drugs may reflect information about the presence of macroorganism resistance determinants. The aim of the work was to isolate the spectrum of oral streptococci from the microbiota of the oral cavity of patients and to determine their sensitivity to a wide range of antibiotics. A total of 342 microbial streptococcal isolates were isolated from saliva samples and a periodontal pocket and tested for antibiotic sensitivity.

[Competence-oriented exam in clinical laboratory diagnostics for students studying in the specialty «Medical Biochemistry».].

In connection with the introduction of annexes and changes to the Federal State Educational Standard of Higher Education in the specialty 30.05.01 «Medical Biochemistry», a need arose to improve the assessment tool of general professional and professional competencies formation in the discipline - clinical laboratory diagnostics.

[Influence of antibiotics on formation of microecology in premature children with low and extremely low body weight at birth].

Aim: Study the influence of antibiotic therapy on the formation of main biotope microflora nasopharynx, large intestine, urinary system) of the premature child organism weighing less than 500 g at birth in hospital.

Materials And Methods: Bacteriological study of upper respiratory tract discharge, urine, large intestine contents in 58 premature children during admission and discharge from newborn and premature children pathology department was carried out. Factor analysis method was applied to construct factor models of antibiotics influence on main biotope microbiocenosis formation.

[The importance of ultrasonic and morphological studies in the differential diagnosis of tumor, dyshormonal and inflammatory diseases of the breast].

The ultrasonic examination results of mammary gland and regional lymph outflow zones were studied in 16,542 patients, including 415 with punction biopsy performance. The mammary gland cancer diagnosis was verified at the cytological examination of bioptic materials in 108 patients.

[Puncture aspiration biopsy under ultrasonic control in the diagnosis of breast neoplasms].

The authors studied the results of sonography of the breast and zones of regional lymph drainage in 15,973 patients. In 154 of them puncture aspiration biopsy was conducted under ultrasonic control. Breast carcinoma was found in 23 patients, in 2 of them the tumor was not palpable.