Postoperative pancreatic fistula risk assessment using digital pathology based analyses at the parenchymal resection margin of the pancreas - Results from the randomized multicenter RECOPANC trial.

Background: In pancreatic surgery Postoperative pancreatic fistula (POPF) represents the most dreaded complication, for which pancreatic texture is acknowledged as one of the strongest predictors. No consensual objective reference has been defined to evaluate the pancreas composition. The presented study aimed to mine histology data of the pancreatic tissue composition with AI assist and correlate it with clinic-pathological parameters derived from the RECOPANC study.

Krüppel-like factor 7 influences translation and pathways involved in ribosomal biogenesis in breast cancer.

Background: Ribosomal biogenesis and ribosomal proteins have attracted attention in the context of tumor biology in recent years. Instead of being mere translational machineries, ribosomes might play an active role in tumor initiation and progression. Despite its importance, regulation of ribosomal biogenesis is still not completely understood.

Long-Term Diabetes Improvement After Duodenal Exclusion in Zucker Diabetic Fatty Rats Is Associated with Prevention of Strain-Specific Pancreatic Remodeling and Increased Beta Cell Proliferation.

Background: Response to metabolic surgery is heterogeneous and the metabolic states that underpin weight loss and metabolic improvement are still unclear. In this study, we investigate parameters of post-bariatric fasting glucoregulation and leverage artificial intelligence-assisted whole-slide image analyses to characterize associated immunohistologic features of the pancreas.

Materials And Methods: We performed either loop duodeno-jejunostomy (DJOS) with exclusion of 1/3 of total intestinal length, loop duodeno-ileostomy with exclusion of 2/3 of total intestinal length (DiOS), or a sham operation on 8-week-old male obese ZDF rats.

Surgeon vs Pathologist for Prediction of Pancreatic Fistula: Results from the Randomized Multicenter RECOPANC Study.

Background: Surgically assessed pancreatic texture has been identified as the strongest predictor of postoperative pancreatic fistula. However, texture is a subjective parameter with no proven reliability or validity. Therefore, a more objective parameter is needed.

[Basis of the algorithm of patient conducting using removable dentures in case of partial teeth loss].

Paper is devoted to the actual problem in stomatology - removable dentures influence upon the intensity of prosthetic bed relief changes. Study of prosthetic bed relief in patients who for 2 years had used plate removable and clasp dental prostheses was done. The most pronounced prosthetic bed relief changes were seen under plate type of prostheses with prolonged defects the least - in patients with plate type of prostheses with short defects.

[Mathematical model of carbon oxide in pressurized chamber during long-term human habitation].

A new approach to quantitative assessment of CO measurements in atmosphere of continuously operating pressurized module GVK-250 has been proposed. It was established that implementation of scheduled operations in the module transform nonstationary CO laws to low-ergodic. The total amount of atmospheric CO decreases substantially as soon as gas emission reaches a low-ergodic condition.

[Evidence based medicine as background for development of stomatological patient report conducting].

Urgent need in methodology of information estimation for true clinical decision taking gave powerful impulse for evidence based medicine concept development that appeared at the end of 80th years. Proved efficacy and safety, optimal correlation of the indices were the stages of the methods and means selection for rationing. In our country such approach found its reflection in developing clinical protocol conducting (standards for doctors), in vitaly important medicines listing and lists of medicines that could be refunded in the system of additional medicine provision.

[Clinical-epidemiological analysis of the results of treatment by non-removable constructions in patients with partial absence of teeth].

In representative clinical-epidemiological study of the results of treatment of the patients with embraced defects of dentitions with non-removable bridge-like constructions having intermediate part of 1 to 3 artificial crowns has revealed risk profiles of complications and defects. It is shown that cumulative portion of complications by remote results for 10-year period reaches 33% for punched-soldered dentures and 10%--for cast dentures. Models of the type of "tree of decisions" for prognosis of non-removable bridge-like dentures are proposed.

[Patient rehabilitation after mandibular reconstruction by revascularized rib autogenous graft with the use of dental implantation].

Deformations after mandibular resection can be eliminated by single stage defects replacement by reconstructive materials of different origin. Prior to microsurgical methods of jaws reconstruction the patient rehabilitation with defects of the jaws had very limited success due to a number of drawbacks of traditional techniques (transplant tendency to resorption and seizure, complexity in surrounding tissues recovery) that makes impossible the use of the dental implantation techniques. In case of interdisciplinary planning of the treatment dental implants can be successfully placed in reconstructed mandible providing the conditions for aesthetic and functional rehabilitation of patients.

[Analysis of conflict situations in orthodontics by Moscow Municipal Committee for Expert Evaluation of Orthodontic Treatment and Denture Making].

The activities of Municipal Committee for Expert Evaluation of Orthodontic Treatment and Fitting with Dentures promote resolution of conflicts: only 5-7% conflict affairs are investigated in the court after investigation in the Committee. A total of 686 patients, mainly with combined maxillofacial diseases, were consulted for 3.5 years of its work.

[Forensic medical expert evaluation in connection with civil actions of patients complaining of improper dental care].

The authors discuss questions facing forensic medical experts in connection with civil "medical" actions. The questions are classified as common and private. Expert evaluations of correspondence of the scope and quality of dental care are offered as the base for analysis of these problems within the framework of civil legislation.

[The orthodontic treatment of traumatic occlusion in sagittal bite anomalies].

A total of 288 patients (100 females and 188 males) aged 25 to 60 with prognathic and progenic occlusion were examined and treated. Dentition deformations were revealed in 182 (63.1%) patients.

[A clinical evaluation of the use of dentures with a Simet glass-ceramic coating].

Positive follow-up results achieved in patients with metal-glass ceramic dentures coated with Simet permit the authors to recommend glass ceramic Simet for wide clinical introduction. In reconstructive dental prosthetics with metal glass ceramic and cermet materials the dentures should be modelled in the articulator. Preventive examinations are recommended once in half a year.

[The clinical evaluation of the use of metal ceramic dentures with a Simet glass-ceramic coating].

Good results of clinical follow-up of patients with cermet dentures coated with cimet (glass ceramic) permit recommending this type of coating for wide practical use. Reconstructive prosthetics with glass ceramic and metal and cermet dentures should involve denture modeling in the articulator and a prophylactic check-up at least once a year with oral hygiene and functional occlusion control.