The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy.

Background: Despite great advances in proliferative diabetic retinopathy (PDR) therapy over the last decades, one third of treated patients continue to lose vision. While resident vitreous macrophages called hyalocytes have been implicated in the pathophysiology of vitreoretinal proliferative disease previously, little is known about their exact role in PDR. In this study, we address molecular and cellular alterations in the vitreous of PDR patients as a means towards assessing the potential contribution of hyalocytes to disease pathogenesis.

Judging robot ability: How people form implicit and explicit impressions of robot competence.

Robots' proliferation throughout society offers many opportunities and conveniences. However, our ability to effectively employ these machines relies heavily on our perceptions of their competence. In six studies (N = 2,660), participants played a competitive game with a robot to learn about its capabilities.

Stingy bots can improve human welfare in experimental sharing networks.

Machines powered by artificial intelligence increasingly permeate social networks with control over resources. However, machine allocation behavior might offer little benefit to human welfare over networks when it ignores the specific network mechanism of social exchange. Here, we perform an online experiment involving simple networks of humans (496 participants in 120 networks) playing a resource-sharing game to which we sometimes add artificial agents (bots).

Artificial intelligence in communication impacts language and social relationships.

Artificial intelligence (AI) is already widely used in daily communication, but despite concerns about AI's negative effects on society the social consequences of using it to communicate remain largely unexplored. We investigate the social consequences of one of the most pervasive AI applications, algorithmic response suggestions ("smart replies"), which are used to send billions of messages each day. Two randomized experiments provide evidence that these types of algorithmic recommender systems change how people interact with and perceive one another in both pro-social and anti-social ways.

STAT3 signaling induced by the IL-6 family of cytokines modulates angiogenesis.

Aberrant angiogenesis is a hallmark of cardiovascular and retinal neovascular disease. The STAT3 signaling pathway represents a potential pharmacological target for these diseases due to its impact on angiogenesis. Surprisingly, some STAT3 activators, such as the IL-6 cytokine family member oncostatin M (OSM), enhance angiogenesis, whereas others, such as ciliary neurotropic factor (CNTF), reduce it.

Facing the FACS-Using AI to Evaluate and Control Facial Action Units in Humanoid Robot Face Development.

This paper presents a new approach for evaluating and controlling expressive humanoid robotic faces using open-source computer vision and machine learning methods. Existing research in Human-Robot Interaction lacks flexible and simple tools that are scalable for evaluating and controlling various robotic faces; thus, our goal is to demonstrate the use of readily available AI-based solutions to support the process. We use a newly developed humanoid robot prototype intended for medical training applications as a case example.

Using Smartphone Sensor Data to Assess Inhibitory Control in the Wild: Longitudinal Study.

Background: Inhibitory control, or inhibition, is one of the core executive functions of humans. It contributes to our attention, performance, and physical and mental well-being. Our inhibitory control is modulated by various factors and therefore fluctuates over time.

Finding the neural correlates of collaboration using a three-person fMRI hyperscanning paradigm.

Humans have an extraordinary ability to interact and cooperate with others. Despite the social and evolutionary significance of collaboration, research on finding its neural correlates has been limited partly due to restrictions on the simultaneous neuroimaging of more than one participant (also known as hyperscanning). Several studies have used dyadic fMRI hyperscanning to examine the interaction between two participants.

Vulnerable robots positively shape human conversational dynamics in a human-robot team.

Social robots are becoming increasingly influential in shaping the behavior of humans with whom they interact. Here, we examine how the actions of a social robot can influence human-to-human communication, and not just robot-human communication, using groups of three humans and one robot playing 30 rounds of a collaborative game ( = 51 groups). We find that people in groups with a robot making vulnerable statements converse substantially more with each other, distribute their conversation somewhat more equally, and perceive their groups more positively compared to control groups with a robot that either makes neutral statements or no statements at the end of each round.

Understanding the Uncanny: Both Atypical Features and Category Ambiguity Provoke Aversion toward Humanlike Robots.

Robots intended for social contexts are often designed with explicit humanlike attributes in order to facilitate their reception by (and communication with) people. However, observation of an "uncanny valley"-a phenomenon in which highly humanlike entities provoke in human observers-has lead some to caution against this practice. Both of these contrasting perspectives on the anthropomorphic design of social robots find some support in empirical investigations to date.

EmotionCheck:: A Wearable Device to Regulate Anxiety through False Heart Rate Feedback.

Previous studies indicate that the way we perceive our bodily signals, such as our heart rate, can influence how we feel. Inspired by these studies, we built EmotionCheck, which is a wearable device that can change users' perception of their heart rate through subtle vibrations on the wrist. The results of an experiment with 67 participants show that the EmotionCheck device can help users regulate their anxiety through false feedback of a slow heart rate.

Mindless Computing: Designing Technologies to Subtly Influence Behavior.

Persuasive technologies aim to influence user's behaviors. In order to be effective, many of the persuasive technologies de-veloped so far relies on user's motivation and ability, which is highly variable and often the reason behind the failure of such technology. In this paper, we present the concept of Mindless Computing, which is a new approach to persuasive technology design.