Purpose: The aim of this study was to assess and compare the arterial uptake of the inflammatory macrophage targeting PET tracer [Cu]Cu-DOTATATE in patients with no or known cardiovascular disease (CVD) to investigate potential differences in uptake.
Methods: Seventy-nine patients who had undergone [Cu]Cu-DOTATATE PET/CT imaging for neuroendocrine neoplasm disease were retrospectively allocated to three groups: controls with no known CVD risk factors (n = 22), patients with CVD risk factors (n = 24), or patients with known ischemic CVD (n = 33). Both maximum, mean of max and most-diseased segment (mds) standardized uptake value (SUV) and target-to-background ratio (TBR) uptake metrics were measured and reported for the carotid arteries and the aorta.
Annu Int Conf IEEE Eng Med Biol Soc
November 2021
Deep learning has gained increased impact on medical classification problems in recent years, with models being trained to high performance. However neural networks require large amounts of labeled data, which on medical data can be expensive and cumbersome to obtain. We propose a semi-supervised setup using an unsupervised variational autoencoder combined with a supervised classifier to distinguish between atrial fibrillation and non-atrial fibrillation using ECG records from the MIT-BIH Atrial Fibrillation Database.
View Article and Find Full Text PDF