A Ni(COD)-free approach for the synthesis of high surface area porous aromatic frameworks.

Porous aromatic frameworks (PAFs) are attractive materials for applications where high surface area and material stability govern performance. Most of the highest surface area PAFs are synthesized using poorly scalable and costly methods involving super-stoichiometric bis(1,5-cyclooctadiene)Nickel(0) (Ni(COD)). This communication describes a general approach for the synthesis of high surface area PAFs that does not use isolated Ni(COD).

Sustained A1 Adenosine Receptor Antagonist Drug Release from Nanoparticles Functionalized by a Neural Tracing Protein.

Respiratory dysfunction is a major cause of death in people with spinal cord injury (SCI). A remaining unsolved problem in treating SCI is the intolerable side effects of the drugs to patients. In a significant departure from conventional targeted nanotherapeutics to overcome the blood-brain barrier (BBB), this work pursues a drug-delivery approach that uses neural tracing retrograde transport proteins to bypass the BBB and deliver an adenosine A1 receptor antagonist drug, 1,3-dipropyl-8-cyclopentyl xanthine, exclusively to the respiratory motoneurons in the spinal cord and the brainstem.

Anisotropic manganese antimonide nanoparticle formation by solution-solid-solid growth mechanism: consequence of sodium borohydride addition towards reduced surface oxidation and enhanced magnetic moment.

A new approach to the solution-phase synthesis of manganese antimonide nanoparticles was developed to reduce competitive oxide formation by exploitation of sodium borohydride (NaBH4) (0.53-2.64 mmol) as a sacrificial reductant.