[Induction of chromosome aberrations and mitotic disorders in a bone marrow cell culture of Papio hamadryas in exposure to cytochalasin B].

A 24-48 hours' treatment with cytocholasin B (1 mg/ml) increases significantly the number of chromosomal aberrations and mitotic abnormalities in primary cultures of bone marrow of the baboon Papio hamadrias. The addition of erythropoietin in concentration of 0.25 units per ml, either before or after the addition of cytochalasin, increases the number of chromosomal aberrations due to hormone stimulation of cell division.