Publications by authors named "Malmsten J"

Although active exploration of environmental information is essential for specifying one's action opportunities in team sports, knowledge about the relationship between visual exploratory behaviour and successful actions in ice hockey is scarce. The purpose of this study was to investigate whether scanning prior to pass reception was associated with a higher probability of a successful outcome of the following action among professional ice hockey players. A total of 43 male and 45 female ice hockey players participated in the study.

View Article and Find Full Text PDF

Background: In recent times, various algorithms have been developed to assist in the selection of embryos for transfer based on artificial intelligence (AI). Nevertheless, the majority of AI models employed in this context were characterized by a lack of transparency. To address these concerns, we aim to design an interpretable tool to automate human embryo evaluation by combining artificial neural networks (ANNs) and genetic algorithms (GA).

View Article and Find Full Text PDF
Article Synopsis
  • Assessing fertilized human embryos for in vitro fertilization is rapidly evolving through artificial intelligence, with a focus on improving prediction accuracy using time-lapse imaging.
  • BELA, a new advanced model, predicts embryo ploidy status effectively without needing embryologists' input, utilizing multitask learning to enhance quality assessments.
  • With a strong performance of 0.76 in distinguishing euploidy from aneuploidy embryos, BELA demonstrates potential for streamlining the embryo evaluation process, although it won't replace existing genetic testing methods.
View Article and Find Full Text PDF

Animals representing a wide range of taxonomic groups are known to select specific food combinations to achieve a nutritionally balanced diet. The nutrient balancing hypothesis suggests that, when given the opportunity, animals select foods to achieve a particular target nutrient balance, and that balancing occurs between meals and between days. For wild ruminants who inhabit landscapes dominated by human land use, nutritionally imbalanced diets can result from ingesting agricultural crops rich in starch and sugar (nonstructural carbohydrates [NCs]), which can be provided to them by people as supplementary feeds.

View Article and Find Full Text PDF

Research Question: What can three-dimensional cell contact networks tell us about the developmental potential of cleavage-stage human embryos?

Design: This pilot study was a retrospective analysis of two Embryoscope imaging datasets from two clinics. An artificial intelligence system was used to reconstruct the three-dimensional structure of embryos from 11-plane focal stacks. Networks of cell contacts were extracted from the resulting embryo three-dimensional models and each embryo's mean contacts per cell was computed.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to assess how well embryologists' rankings of embryos matched with those generated by eight AI algorithms using time-lapse videos and single embryo images from 100 patient cycles.
  • Embryologists showed a good level of agreement among themselves (average Kendall's τ of 0.70), but there was lower agreement with AI algorithms (average K-τ of 0.53), highlighting varying reliability among the AI methods.
  • While embryologists were more consistent in identifying the top embryos, achieving 59.5% agreement on the best-quality embryo, the most successful AI algorithms only reached 40.3%, with two of the algorithms showing particularly poor performance.
View Article and Find Full Text PDF
Article Synopsis
  • Advances in AI and deep learning are transforming embryo quality assessment in IVF, focusing on optimizing time-lapse imaging for better predictions.
  • The new model, BELA (Blastocyst Evaluation Learning Algorithm), outperforms previous methods by utilizing multitask learning to assess embryo quality without reliance on embryologists' subjective input.
  • BELA achieves a 0.76 AUC for identifying euploidy vs. aneuploidy, streamlining the evaluation process and reducing the workload for embryologists, although it does not replace genetic testing for aneuploidy.
View Article and Find Full Text PDF

Purpose: To evaluate embryo ploidy in a cohort of patients who underwent preimplantation genetic testing for aneuploidy (PGT-A) with vitrified oocytes compared to fresh oocytes.

Methods: Patients who underwent their first autologous oocyte vitrification and warming followed by in vitro fertilization (IVF) and trophectoderm biopsy for PGT-A between 1/1/2017 and 12/31/2021 at a single academic institution were included. Patients were compared 1:3 to age-matched controls who underwent their first IVF cycle with fresh oocytes and subsequent trophectoderm biopsy for PGT-A.

View Article and Find Full Text PDF
Article Synopsis
  • The study addresses challenges in selecting viable embryos for in-vitro fertilization (IVF) by comparing existing assessment methods, highlighting their limitations.
  • Researchers developed an AI-based system called STORK-A, which non-invasively predicts embryo ploidy status using a comprehensive dataset of over 10,000 embryos, including images and clinical information.
  • Initial findings show STORK-A achieved 69.3% accuracy in distinguishing aneuploid from euploid embryos, suggesting promising potential for more effective embryo evaluation in IVF.
View Article and Find Full Text PDF

Objective: To determine the ongoing pregnancy rate among patients with infertility with a low antimüllerian (AMH) level compared with those with a normal AMH level after oral and injectable ovulation induction (OI)/intrauterine insemination (IUI).

Design: Retrospective cohort.

Setting: Academic center.

View Article and Find Full Text PDF

Gestation and lactation have high energetic requirements. Up to three-fourths of the gestation period in moose (Alces alces) overlaps with the food-scarce period in winter. During this period, moose deal with the limited forage resources available through hypometabolism with decreased heart rate and body temperature (T).

View Article and Find Full Text PDF

Objective: To perform a series of analyses characterizing an artificial intelligence (AI) model for ranking blastocyst-stage embryos. The primary objective was to evaluate the benefit of the model for predicting clinical pregnancy, whereas the secondary objective was to identify limitations that may impact clinical use.

Design: Retrospective study.

View Article and Find Full Text PDF

At northern latitudes, large spatial and temporal variation in the nutritional composition of available foods poses challenges to wild herbivores trying to satisfy their nutrient requirements. Studies conducted in mostly captive settings have shown that animals from a variety of taxonomic groups deal with this challenge by adjusting the amounts and proportions of available food combinations to achieve a target nutrient balance. In this study, we used proportions-based nutritional geometry to analyze the nutritional composition of rumen samples collected in winter from 481 moose () in southern Sweden and examine whether free-ranging moose show comparable patterns of nutrient balancing.

View Article and Find Full Text PDF

Objective: To convert blastocyst (BL) morphological grade and BL day into a numeric blastocyst score (BS).

Design: Retrospective cohort study.

Setting: Academic center.

View Article and Find Full Text PDF

Severe cardiomegaly with an atrial septal defect was discovered during necropsy of a subadult White-tailed Eagle (Haliaeetus albicilla) found dead in the wild. A thin membrane composed of fibromuscular tissue separated the left atrium into two chambers, most consistent with that described for cor triatriatum sinister (CTS) in other species. Seventeen months later, necropsy of an adult White-tailed Eagle again revealed CTS.

View Article and Find Full Text PDF

Snow leopards inhabit the cold, arid environments of the high mountains of South and Central Asia. These living conditions likely affect the abundance and composition of microbes with the capacity to infect these animals. It is important to investigate the microbes that snow leopards are exposed to detect infectious disease threats and define a baseline for future changes that may impact the health of this endangered felid.

View Article and Find Full Text PDF

Artificial intelligence (AI) systems have been proposed for reproductive medicine since 1997. Although AI is the main driver of emergent technologies in reproduction, such as robotics, Big Data, and internet of things, it will continue to be the engine for technological innovation for the foreseeable future. What does the future of AI research look like?

View Article and Find Full Text PDF

In northern environments, the period of access to high-quality forage is limited, exerting strong selective pressure to optimize the timing of parturition. We analysed timing and variation in moose () parturition dates of 555 females at 18 study sites across 12° of latitude (56-68° N, 1350 km) in Sweden. We found evidence for a spatial match of parturition timing to vegetation onset, but no evidence that moose adjust parturition to vegetation onset in a given year.

View Article and Find Full Text PDF

Diet quality is an important determinant of animal survival and reproduction, and can be described as the combination of different food items ingested, and their nutritional composition. For large herbivores, human landscape modifications to vegetation can limit such diet-mixing opportunities. Here we use southern Sweden's modified landscapes to assess winter diet mixtures (as an indicator of quality) and food availability as drivers of body mass (BM) variation in wild moose (Alces alces).

View Article and Find Full Text PDF

Visual morphology assessment is routinely used for evaluating of embryo quality and selecting human blastocysts for transfer after in vitro fertilization (IVF). However, the assessment produces different results between embryologists and as a result, the success rate of IVF remains low. To overcome uncertainties in embryo quality, multiple embryos are often implanted resulting in undesired multiple pregnancies and complications.

View Article and Find Full Text PDF

: Snow leopards, , are a threatened apex predator, scattered across the mountains of Central and South Asia. Disease threats to wild snow leopards have not been investigated.: Between 2008 and 2015, twenty snow leopards in the South Gobi desert of Mongolia were captured and immobilised for health screening and radio-collaring.

View Article and Find Full Text PDF

Postmortem body temperature is used to estimate time of death in humans, but the available models are not validated for most nonhuman species. Here, we report that cooling in an adult female moose () equipped with a rumen temperature monitor was extremely slow, with a rumen temperature of 27-28 C as late as 40 h postmortem.

View Article and Find Full Text PDF

Climate change, with warmer temperatures and altered precipitation patterns, has affected the distribution of vectors and vector-borne diseases. In the northern hemisphere, vectors are spreading north, and with them, pathogens of zoonotic and animal health impact. Eurasian moose (Alces alces alces) are physiologically and anatomically adapted for cold climate, and are rarely considered ideal hosts of vectors, apart from deer keds (Lipoptena cervi).

View Article and Find Full Text PDF

Intraperitoneal radio transmitters have been widely used in free-ranging wild mammals, but there are no long-term studies on their biocompatibility or technical stability within the abdominal cavity of animals. Possible negative health effects may bias results from ecological studies on instrumented animals and raise concerns over animal welfare issues. The aim of this study was to evaluate the long-term technical stability and pathological effects of Telonics intraperitoneal very high frequency (VHF) radio transmitters in brown bears ().

View Article and Find Full Text PDF