Anti-inflammatory and varicocele treatment in nonobstructive azoospermia.

A 34-year-old male patient with nonobstructive azoospermia and childlessness for more than 2 years is presented. As even severely damaged testes often harbour cryptic areas with remaining spermatogenesis, such cases might be suitable for spermatid extraction from bilateral testicular biopsies. Taking into account that testicular biopsies bear the risk of permanent testosterone insufficiency, less invasive andrological treatment modalities were considered.

Preclinical evaluation of inducible nitric oxide synthase lipoplex gene therapy for inhibition of stent-induced vascular neointimal lesion formation.

Several reports have established the concept of nitric oxide synthase (NOS) gene transfer for inhibiting smooth muscle cell (SMC) proliferation after vascular injury. To minimize potential risks associated with viral gene transfer, we developed a liposome-based gene transfer approach employing inducible NOS (iNOS) overexpression for inhibition of stent-induced neointimal lesion formation. Therapeutic lipoplexes were transferred to femoral or coronary arteries of Goettingen minipigs, using the Infiltrator local drug delivery device.

Noninvasive investigation for renal artery stenosis: contrast-enhanced magnetic resonance angiography and color Doppler sonography as compared to digital subtraction angiography.

Introduction: The question about the most appropriate non-invasive method for detecting a renal artery stenosis (RAS) when comparing contrast enhanced magnetic resonance angiography (MRA) and color Doppler sonography (CDS) is still under discussion. Therefore we conducted a prospective study in order to evaluate both methods as compared to digital subtraction angiography (DSA).

Patients/methods: Thirtysix consecutive patients (53,9 +/- 13,7 years) with suspected RAS were investigated.

Post-transplant distal-limb bone-marrow oedema: MR imaging and therapeutic considerations.

Background: In recent years a previously unrecognized pain syndrome of the distal lower limbs after organ transplantation has been noted. A relationship to cyclosporin A was suspected, but no clear aetiology and pathogenesis have been established.

Methods: During the last 30 months we diagnosed the pain syndrome in 10 patients after renal transplantation.

Effect of acute intravenous ace-inhibition on the intrarenal doppler flow characteristics in hypertensive patients with and without unilateral renal artery stenosis.

Assessment of intrarenal doppler signals is of particular importance in screening for renal artery stenosis. We studied the effect of acute ACE-inhibition (1,25 mg enalaprilate i.v.

[Cystic liver tumor resembling echinococcosis].

The hepatobiliary cytadenoma or -carcinoma is a cystic, multilocular, intrahepatic tumor in the liver affecting mainly middle-aged people. In most cases hepatobiliary cystadenomas or -carcinomas cannot be definitely differentiated by sonography and CT from other cystic lesions in the liver. Resection of the tumorous parts of the liver as early as possible is essential for the prognosis for the patients because malignant transformation of the lesions might occur.

Reliability and validity of noninvasive imaging of internal carotid artery pseudo-occlusion.

Background And Purpose: Our study evaluated noninvasive tests for the diagnosis of atheromatous internal carotid artery (ICA) pseudo-occlusion.

Methods: Twenty patients (17 men, 3 women; mean age +/-SD, 64.3+/-11.

Venous incompetence in erectile dysfunction: evaluation with color-coded duplex sonography and cavernosometry/-graphy.

The purpose of this study was to assess the accuracy of multi-parameter measurements with color-coded duplex sonography (CCDS) for the diagnosis of venous leakage in patients with erectile dysfunction. Sixty patients with repeated unsatisfactory reactions after intracavernous injection of vasoactive substances underwent CCDS. Following intracavernous injection of prostaglandin E1, peak systolic velocity (PSV), enddiastolic velocity (EDV), time averaged velocity (TAV), resistance index (RI), and pulsatility index (PI) were measured in the cavernous arteries over 30 min (one measurement per minute).

[B-mode ultrasound and modern Doppler ultrasound methods in diseases of the thyroid gland and parathyroid glands].

Color-coded duplex sonography is the main innovation in diagnostic ultrasound in recent years. It allows quantification of tissue vascularity and appreciation of vascular morphology. Due to the unique thyroid hypervascularity in Graves' disease this diagnosis can be made with color Doppler sonography alone.

[Possibilities for dose reduction in coronal spiral CT of the mid-face area].

The radiation dose at the eye lens and the thyroid gland in spiral-CT-examinations is comparable to those known from conventional computed tomography. In view of an increasing artificial radiation exposure, it remains an important aim to achieve dose reduction with persistent adequate imaging quality. We determined the doses of the named organs in four different CT-examination protocols by use of phantom studies and in 45 patients.

Transjugular intrahepatic portosystemic shunts: improved evaluation with echo-enhanced color Doppler sonography, power Doppler sonography, and spectral duplex sonography.

Objective: We assessed the feasibility of contrast-enhanced color Doppler, power Doppler, and spectral duplex sonography for visualization and quantification of flow through transjugular intrahepatic portosystemic shunts (TIPS) in patients in whom the baseline sonographic evaluation was unsatisfactory.

Subjects And Methods: Thirty-three patients underwent color Doppler, power Doppler, and spectral duplex sonography after TIPS insertion or before TIPS revision (mean time interval +/- SD, 1 +/- 1 day). All sonograms were obtained before and after patients received echo-enhancing contrast material.

[Glomerulonephritis and malignant lymphoma. Mostly men with low-grade lymphoma with various forms of glomerulonephritis].

Background: The association of non-Hodgkin's lymphoma with different types of glomerulonephritis is well-known for many years. Whereas in Hodgkin's disease, minimal change glomerulonephritis is mainly observed, in non-Hodgkin's lymphoma various forms of glomerulonephritis are found.

Patients And Results: We describe 3 cases of non-Hodgkin's lymphoma, which were associated with glomerulonephritis.

[Radiologic diagnosis of primary extranodal lymphoma manifestations].

Primary extranodal lymphoma manifestation in the narrow sense is the term used to define the primary organ manifestation of a malignant lymphoma, excluding the thymus, spleen, Waldeyer's tonsillar ring, the appendix and Peyer's patches. However, in the clinical routine the term is also used for the secondary organ manifestation of underlying lymphoproliferative disease. Primary extranodal lymphomas are mainly non-Hodgkin lymphomas; there is primary extranodal manifestation of Hodgkin's disease in only about 1% of the cases.

Accuracy of pedicle screw placement in lumbar vertebrae.

Study Design: The location of pedicle screws (n = 42) in four human specimens of the lumbar spine and in 30 patients (n = 131 screws) after lumbar spinal fusion was assessed using computed tomography.

Objectives: To determine the accuracy of pedicle screw placement in lumbar vertebrae and the reproducibility and repeatability of the computed tomography examination.

Summary Of Background Data: Failures in the placement of transpedicular screws for lumbar fusion are reported.

Fast spin-echo MR imaging of the pediatric brain.

On a 1.5-T MR unit conventional spin-echo (CSE) and fast spin-echo (FSE) images were obtained in 70 consecutive children ranging from 4 days to 13 years in age. They suffered from developmental retardation, neurodegenerative, ischemic or inflammatory diseases.

Diagnosis and treatment of a solitary infected hepatic cyst in two patients with adult polycystic kidney disease.

We report on two women (one 52-year-old who underwent kidney transplantation 15 months ago and the other, 71-year-old, undergoing hemodialysis) both with adult polycystic kidney disease who had to be hospitalized because of recurrent fever attacks up to 40 degrees C without any remarkable abdominal symptoms. Staphylococcus hominis and E. coli were recovered respectively from blood cultures of both patients.

[Bilateral pneumothorax, pneumomediastinum and pneumoperitoneum following unilateral percutaneous lung biopsy].

Case report on a 53-year old male patient; after transthoracic resection of the oesophagus a unilateral percutaneous biopsy of a newly developed round focus of the lung led to a bilateral pneumothorax (as well as a pneumomediastinum and a pneumoperitoneum). After transthoracic surgery the described alterations have also to be taken into account as possible complications of a unilateral percutaneous lung-biopsy.

[Accuracy of pedicle screws following instrumented dorsal fusion of the lumbar spine].

We evaluated the placement of pedicle screws (N = 131) in 30 patients after lumbar dorsal spinal fusion. Postoperatively all patients were examined by CT. 39.

[FCR AC-1: prototype of a new generation of equipment for digital luminescence radiography (DLR)].

The promising perspective to integrate the project-image-radiography into future picture archiving and communication systems (PACS) failed in medium terms because of high costs. A new generation of compact computed radiography systems (CR) facilitate the entry into storage phosphorus technique for routine application while future PACS-connection is still possible. In August 1990 the Institute of Diagnostic Radiology (University of Düsseldorf) received the first FCR AC-1 in Germany for clinical trials.

[Renal stent implantation. The current indications, 2-year results and the possibilities for percutaneous stent recovery].

Use of the Strecker flexible balloon-expandable tantalum stent for treatment of renal artery stenosis after failed angioplasty or transaortic thrombendarterectomy was evaluated in 18 patients (17 hypertensive, 1 normotensive). Right (n = 10) and left (n = 6) renal arteries were involved; in 2 patients renal artery stenosis had developed after kidney transplantation. Indications for stent placement were inadequate immediate postangioplasty response (n = 16), and obstructing intimal flaps following transaortic endarterectomy (n = 2).

[Digital luminescence and conventional radiography in laryngeal and pharyngeal diagnosis].

Double-contrast examination of the pharynx using a modified Valsalva maneuver to achieve full distension of pharyngeal structures, is safe and easy. Conventional screen-film radiographs are compared with storage phosphor digital images and the value of this examination is illustrated by case reports.