Insights into allergic risk factors from birth cohort studies.

Objective: To present an update of birth cohort study designs and their contributions to allergic risk.

Data Sources: The PubMed database was used to search for relevant articles.

Study Selections: Peer-reviewed prospective and retrospective studies involving the assessment of allergy using human birth cohorts between 2014 and 2021 were evaluated.

Exposomal research in the context of birth cohorts: What have they taught us?

Objective: To review birth cohorts with an exposomal approach and their key outcomes and challenges. Exposome encompasses all human environmental exposures from conception onward. The impact of environmental exposures is greatest in critical stages of life, including fetal and early childhood.

Prenatal and early-life exposure to indoor air-polluting factors and allergic sensitization at 2 years of age.

Background: Previous studies have suggested that exposures to indoor air-polluting factors during pregnancy and early life can influence childhood allergy development. These exposures have been investigated in singularity; however, the effect of simultaneous exposure to multiple factors remains unclear.

Objective: To evaluate the effect of prenatal and early-life exposure to 7 air-polluting factors on allergic sensitization at 2 years of age.