VEGF Expression to Support Targeted Therapy in Ovarian Surface Epithelial Neoplasms.

Introduction: Vascular Endothelial Growth Factor (VEGF), a promoter of angiogenesis, is a promising target for anti-angiogenic therapy in ovarian cancer. In our study, we examined the expression of VEGF in the spectrum of epithelial ovarian neoplasms (benign, borderline and malignant) by Immunohistochemistry (IHC).

Aim: Diagnosing ovarian epithelial neoplasms, examining the expression of VEGF in benign, borderline and malignant neoplasms and correlating it with histological grade and stage of malignant cases.

Goblet cell carcinoid of appendix: A rare case with literature review.

Introduction: The goblet cell carcinoid, a rare tumor of the appendix, is a separate entity from adenocarcinoma and carcinoid tumors.

Presentation Of Case: We report a case of goblet cell carcinoid in our institute who presented with acute abdominal symptoms simulating acute appendicitis.

Discussion: Goblet cell carcinoid is a rare neoplasm with distinct histological and clinical features.

Machine learning approach for automated screening of malaria parasite using light microscopic images.

The aim of this paper is to address the development of computer assisted malaria parasite characterization and classification using machine learning approach based on light microscopic images of peripheral blood smears. In doing this, microscopic image acquisition from stained slides, illumination correction and noise reduction, erythrocyte segmentation, feature extraction, feature selection and finally classification of different stages of malaria (Plasmodium vivax and Plasmodium falciparum) have been investigated. The erythrocytes are segmented using marker controlled watershed transformation and subsequently total ninety six features describing shape-size and texture of erythrocytes are extracted in respect to the parasitemia infected versus non-infected cells.

Malignant phylloides tumor of breast in a pregnant woman with coincidental nulliparous vaginal prolapse.

Malignant phylloides tumor is a relatively rare and rapidly growing tumor of the breast. Presentation during pregnancy is uncommon. Reports regarding malignancy in these tumors differ greatly in incidence, and most of them are stromal malignancies.

Leiomyoma of kidney: An Indian experience with literature review.

Introduction: Leiomyoma of kidney is an exceptional finding in the urinary tract. Though most of these tumors are detected on autopsy, still it remains a diagnostic challenge.

Presentation Of Case: We report three adult cases of renal leiomyoma in our institute who presented with abdominal mass and haematuria in last 8 years.

Primary squamous cell carcinoma of breast with ipsilateral axillary lymph node metastasis: An unusual case.

Introduction: Pure squamous cell carcinoma of the breast [SCCB] is rare.

Presentation Of Case: We report a case of primary squamous cell carcinoma of breast with ipsilateral axillary lymph node metastasis in a 58year old woman.

Discussion: It is a breast carcinoma entirely composed of metaplastic squamous cells that may be keratinized, non-keratinized or spindled.

Multiple generalized xanthogranuloma in adult: case report and treatment.

Xanthogranuloma is a benign, asymptomatic, and self-healing disorder of non-Langerhans cell histiocytosis, affecting mostly infants, children, and rarely adults. Diagnosis is easy in typical cases but become more complex in unusual forms. We report a case of a 28-year-old male patient who presented with multiple diffuse brown-to-yellowish papulonodular eruptions over extremities, ears, face, trunk, and extensors of joints with almost bilaterally symmetrical distribution for a period of one month.

Migratory polyarthritis in familial hypercholesterolemia (type IIa hyperlipoproteinemia).

Metabolic disorders are often encountered in clinical practice. Some of these diseases are associated with dermatological and musculoskeletal manifestations. Familial hypercholesterolemia is a disorder of lipoprotein metabolism characterized by elevated cholesterol, low-density lipoprotein cholesterol, xanthomas and early onset atherosclerosis.