Temperature-dependent dynamics of energy stores in Drosophila.

Background: Understanding how ectotherms manage energy in response to temperature is crucial for predicting their responses to climate change. However, the complex interplay between developmental and adult thermal conditions on total energy stores remains poorly understood. Here, we present the first comprehensive quantification of this relationship in Drosophila melanogaster, a model ectotherm, across its entire thermal tolerance range.

Developmental plasticity of thermal performance curve for reproduction in Drosophila melanogaster.

In ectotherms, body temperature is a crucial determinant of performance and fitness, as captured by thermal performance curves (TPCs). Since survival in variable environments is often facilitated by phenotypic plasticity, to reliably assess an organism's ability to cope with thermal changes, it is necessary to characterize not only TPCs but also their reaction norms. While previous studies have investigated plasticity in TPCs, these studies focus only on selected parameters and a few developmental temperatures.

Antioxidant and Antidiabetic Activities, and UHPLC-ESI-QTOF-MS-Based Metabolite Profiling of an Endophytic Fungus Nigrospora sphaerica BRN 01 Isolated from Bauhinia purpurea L.

Diabetes-associated postprandial hyperglycemia is a major risk factor in cardiovascular disease. Since enzyme α-glucosidase is primarily responsible for glucose release during digestion, inhibiting it mitigates post-meal spike in blood glucose level. Metabolites from endophytic fungi could be potential natural inhibitors of this enzyme.