Mixed cobalt(III) complexes with aromatic amino acids and diamine. Part IV. Influence of noncovalent intra-and interligand interactions on rotamer population of the S-phenylalaninato and S-tyrosinato side groups in (1,2-diaminoethane)bis-(S-aminocarboxylato)cobalt(III) complexes.

Rotamer population of S-tyrosinato and S-phenylalaninato ligands side groups in diastereomers of (1,2-diaminoethane)bis-(S-aminocarboxylato)cobalt(III) complexes is calculated by vicinal alpha and beta proton coupling constant analysis. The effect of noncovalent intra- and interligand interactions on the population of rotamers in D20 solution is discussed. It has been established that in all the complexes investigated the most abundant is rotamer t, in which aromatic voluminous moiety and carboxylic group are in an anti position.

Mixed cobalt(III) complexes with aromatic amino acids and diamines. III. Absolute structure of Lambda-trans(O)-(1,2-diaminoethane-kappa(2)N,N)bis(S-tyrosinato)cobalt(III) chloride tetrahydrate.

The title compound, [Co(C(9)H(10)NO(3))(2)(C(2)H(8)N(2))]Cl.4H(2)O, is one of six possible diastereomers of the (1,2-diaminoethane)bis(S-tyrosinato)cobalt(III) complex. The cobalt(III) ion has an octahedral coordination, with three five-membered chelate rings which have deformed coordination angles and coordinated O atoms in trans positions.

Mixed cobalt(III) complexes with aromatic amino acids and diamine. Part II. Synthesis and configuration of (1,2-diaminoethane)bis(L-tyrosinato)cobalt(III)complex diastereomers. The crystal structure of the delta-C1-cis(O) diastereomer.

In the reaction of trans-[CoCl2(en)2]+ with L-tyrosine all six theoretically possible diastereomers of the (1,2-diaminoethane)bis(L-tyrosinato)cobalt(III) complex were formed. The following five were isolated: gamma-trans(O); and gamma- and delta-C2-cis(O) and gamma- and delta-C1-cis(O) diastereomers, while the delta-trans(O) diastereomer was only detected in the corresponding eluate. Separation of the obtained diastereomers was performed by chromatography on a Dowex 1 x 4 column.

Variation in survival in coastal and continental regions of Croatia--results of a longitudinal study.

After 25 years of follow-up, regional variations in survival were analysed on a sample of 3343 participants (1780 female, 1563 male) from three urban and three rural municipalities in Croatia. Age of participants was in the range 35-54 years at the beginning of the study (1969). Cox regression for general mortality singled out one continental rural municipality (Virovitica) with the lowest survival in both genders.

Cognitive evoked potentials VEP P300 persons occupationally exposed to low concentrations of toluene.

Cognitive evoked potentials VEP P300 were examined in 49 workers at printing press occupationally exposed to low concentrations of toluene for averagely 20 years, and in 59 control subjects. The exposure level of toluene was evaluated in randomly selected subgroups comprising 36 exposed and 27 control subjects. The concentrations of toluene were measured in peripheral blood on Wednesday morning before entering the work area, while the hippuric acid in urine was measured before and after entering the work area.

The use of visual evoked potentials to follow-up prisoners of war after release from detention camps.

Visual evoked potentials were examined in released prisoners of war (POWs) in order to evaluate the extent of neurological impairment after imprisonment in Serbian detention camps. On two occasions visual evoked potentials were determined in a group of 11 released prisoners of war (POWs): 157 days and 379 days after release from detention camp. During the first examination no significant differences were found in VEP parameters between the right and left eye.

Brain stem evoked potentials and visual evoked potentials in relation to the length of occupational exposure to low levels of toluene.

In 49 printing-press workers occupationally exposed to toluene for approximately 21.6 years, the values of BEAP and VEP parameters were examined in relation to the length of exposure. With the exception of P2 wave, there was a significant increase in the latencies of all the BEAP waves examined as well as in the interpeak latency (IPL) P3-P4, whereas IPL P4-P5 decreased significantly with the length of exposure.

Brainstem auditory evoked potentials in individuals exposed to long-term low concentrations of toluene.

Brainstem auditory evoked potentials (BAEPs) were examined in 49 workers employed in a printing press, who were occupationally exposed to low concentrations of toluene for an average of 20.3 years, and in 59 subjects in a control group. In the group of exposed workers, a significant decrease was found in all wave amplitudes examined, a significant prolongation of P1 wave latency, and an increased interval of interpeak latencies (P3-P5), indicating that the extramedullary and high medullary part of the auditory pathway are biologically most frequently affected by chronic exposure to low concentrations of toluene.

Visual evoked potentials in relation to factors of imprisonment in detention camps.

Visual evoked potentials (VEPs) of the pattern shift reversal type were determined in a representative group of 57 prisoners of war (POWs) released in 1992 from detention camps in former Yugoslavia. The parameters were correlated with the conditions in four camps (1-4). All subjects were male, with a mean age of 34.

Visual evoked potentials in two groups of prisoners of war after release from Serbian detention camps.

Visual evoked potentials (VEP) were determined in two groups of released prisoners of war (POWs) from Serbian detention camps during the war in Croatia 1991/92. The first group comprised 22 POWs (group I), examined 10 to 60 days after release, and the second group comprised 24 POWs (group II), examined 6 to 9 months after release. The third group comprised 36 control subjects.

Visual evoked potentials in individuals exposed to long-term low concentrations of toluene.

An investigation of visual evoked potentials was carried out in two groups of subjects; 49 workers employed in a printing-prss where toluene has been used exclusively as an organic solvent for the last 30 years, and 59 workers not occupationally exposed to any known neurotoxic substances. The average length of work service in the printing-press was 21.4 years.

Loss of body mass in ex-prisoners of war.

Body mass was examined in the defenders of Vukovar (n = 71) from eastern Slavonia, Republic of Croatia, immediately on release from enemy concentration camps. The sample consisted of a group of 33 male smokers who had been imprisoned for (mean +/- SD) 127.4 +/- 18.

[Reevaluation of work disability in chronic bronchitis and functional criteria at rest].

As part of an investigation to reassess disability which was performed in 579 subjects with an internist's diagnosis, disability was reassessed in 68 males with chronic bronchitis as the main diagnosis. Disability reassessment was carried out by an informal team of physicians consisting of pulmologists and members of a second degree disability board. The aim of the study was to define the differences between disability reevaluation and residual working capacity.