Bitumen exhibits viscoelastic properties, showcasing both viscous and elastic behaviors, which are characterized by the phase angle and dynamic modulus. Issues like early fatigue fractures, rutting, and permanent deformations in bituminous asphalt pavements arise due to moisture susceptibility, high-temperature deformation, low-temperature cracking, and overloading. These distresses result in potholes, alligator cracks, and specific deformations that lead to early pavement failure, increasing rehabilitation and maintenance costs.
View Article and Find Full Text PDFIntroduction: Research shows that medical students are graduating with inadequate teaching on diverse patients and insufficient experience of working with diverse patient groups. The inclusion of patients from diverse groups is necessary in healthcare teaching to ensure medical students are adequately prepared for practice. In this study, we explored the perspectives of General Practitioner (GP) tutors on the recruitment of diverse volunteer patients for medical student primary clinical care placements.
View Article and Find Full Text PDFCurr Probl Cardiol
December 2024
Interventional cardiology is on the cusp of a significant transformation as we approach 2050, driven by emerging trends and groundbreaking technological innovations. This mini review explores the pivotal developments shaping the field, focusing on three key areas: Emerging Trends in Interventional Cardiology, Technological Innovations: The Next Frontier, and the Future Era of Intervention Cardiology from 2024 to 2050. Emerging trends, including advancements in imaging and artificial intelligence, are revolutionizing diagnosis and treatment, allowing for more precise and personalized interventions.
View Article and Find Full Text PDFThere is a global concern with continuous waste production, and efforts are underway to use these wastes in the construction sector. The negative effects of excessive waste production and the use of virgin materials and energy in Hot Mix Asphalt (HMA) construction are challenging and require attention. The right step towards developing resilient road infrastructure is using cold bitumen emulsion mixtures (CBEMs), a cold mix asphalt (CMA).
View Article and Find Full Text PDFMild hyperthermia (MHTh) is often used in combination with chemotherapy and radiotherapy for cancer treatment. In the current study, the effect of MHTh on the enhanced uptake of the FDA-approved chemotherapy drug, liposomal doxorubicin (dox) in syngeneic 4T1 tumors was investigated. Doxorubicin has inherent fluorescence properties having an emission signal at 590 nm upon excitation with a 480 nm laser.
View Article and Find Full Text PDFCeramics are the oxides of metals and nonmetals with excellent compressive strength. Ceramics usually exhibit inert behavior at high temperatures. Magnesium aluminate (MgAl2O4), a member of the ceramic family, possesses a high working temperature up to 2000°C, low thermal conductivity, high strength even at elevated temperatures, and good corrosion resistance.
View Article and Find Full Text PDFRecent research has shed light on the culpability of LA (left atrial) abnormality, in the form of atrial cardiopathy, as an independent risk factor for the development of atrial fibrillation, LA thrombus and subsequent stroke. The aim of this study was to measure LA electromechanical dissociation (EMD), LA volumes, P-wave dispersion (PWD) and P-wave terminal force in V1 (PTFV1) as markers of atrial cardiopathy in patients with ESUS (embolic stroke of undetermined source), to determine whether atrial cardiopathy is an integral part in the causal pathway of ESUS. 28 patients presenting with ischemic stroke and fulfilling the criteria for ESUS were enrolled into this cross-sectional, observational study along with a control group of 28 age- and gender-matched apparently healthy individuals.
View Article and Find Full Text PDFAtrial fibrillation (AF) is widely considered to be the most prevalent cardiac arrhythmia with an incidence of roughly 1%-2% in the United States alone. The incidence of AF has been known to increase with advancing age and thus presents a significant burden on healthcare systems across the globe. AF arises as a result of several mechanisms including structural changes that occur in the heart over time.
View Article and Find Full Text PDFHybrid composites of molybdenum disulfide (MoS), graphene nanoplatelets (GNPs) and polyaniline (PANI)/polypyrrole (PPy) have been synthesized as cost-effective electrode materials for supercapacitors. We have produced MoS from molybdenum dithiocarbamate by a melt method in an inert environment and then used a liquid exfoliation method to form its composite with graphene nanoplatelets (GNPs) and polymers (PANI and PPy). The MoS melt/GNP ratio in the resultant composites was 1 : 3 and the polymer was 10% by wt.
View Article and Find Full Text PDFAcquired hemophilia A (AHA) is a bleeding disorder, autoimmune in nature, in which the body produces IgG antibody inhibitors that attack coagulation factor VIII, causing deficiency. It is largely seen in the elderly, but most cases are idiopathic. Cases of acquired hemophilia A can occur in the presence of neutrophilia, infection, acute physiological stress, medication effect, tissue necrosis, various inflammatory disorders, and/or malignancy, which presents a formidable challenge with clinical workup.
View Article and Find Full Text PDFFeedback-based wavefront shaping is a promising and versatile technique for enhancing the contrast of a target signal for both coherent and incoherent light through a highly scattering medium. However, this technique can fail for a dynamic sample with a short correlation time. So far, most proposed methods for high-speed wavefront shaping can only directly enhance the intensity of coherent light but not incoherent light.
View Article and Find Full Text PDFIntroduction: We previously reported that systemic delivery of dystrophin expressing chimeric (DEC) cells of normal () and dystrophin-deficient () myoblast (MB) or mesenchymal stem cell (MSC) origin restored dystrophin expression and improved cardiac function in the mouse model of Duchenne muscular dystrophy (DMD).
Aim: This study evaluated the effect of intraosseous delivery of murine DEC lines of MB (MB /MB ) and MSC (MB /MSC ) origin on function of gastrocnemius muscle (GM).
Material And Methods: DEC lines created by fusion were tested in the mouse model of DMD: Group 1 - vehicle (control), Group 2 - non-fused 0.
Environ Sci Pollut Res Int
February 2023
The generation of waste materials is a global concern and attempts are being made to utilize these wastes in the construction industry. The development of road infrastructure everywhere is going at a fast pace which increases the environmental degradation, fossil fuel consumption, global warming, and depletion of natural materials because of hot mix asphalt (HMA) usage. The detrimental effects of generation of waste in large quantities at a global scale and virgin material/energy consumption in HMA construction are of prime concern and need to be addressed.
View Article and Find Full Text PDFPavement design is a long-term structural analysis that is required to distribute traffic loads throughout all road levels. To construct roads for rising traffic volumes while preserving natural resources and materials, a better knowledge of road paving materials is required. The current study focused on the prediction of Marshall stability of asphalt mixes constituted of glass, carbon, and glass-carbon combination fibers to exploit the best potential of the hybrid asphalt mix by applying five machine learning models, i.
View Article and Find Full Text PDFCoronary artery anomalies are relatively uncommon in the general population with a roughly 1% incidence. Though oftentimes asymptomatic, these anomalies can be detrimental, resulting in myocardial infarction and even sudden cardiac death. Here, we present a case in which a 65-year-old male presented to the emergency room with substernal chest pain that radiated into his left arm.
View Article and Find Full Text PDFSignificance: Deep tissue noninvasive high-resolution imaging with light is challenging due to the high degree of light absorption and scattering in biological tissue. Photoacoustic imaging (PAI) can overcome some of the challenges of pure optical or ultrasound imaging to provide high-resolution deep tissue imaging. However, label-free PAI signals from light absorbing chromophores within the tissue are nonspecific.
View Article and Find Full Text PDFSingle pixel spectroscopy based on Hadamard transform (SPS-HT) has been applied widely because of its capability of wavelength multiplexing and associated advantage in signal-to-noise ratio. In this paper, we propose a sequency encoding single pixel spectroscopy (SESPS) based on two-dimensional (2D) masks for concurrent coding of all Hadamard coefficients instead of one-dimensional (1D) Hadamard masks (only coding one coefficient at a time) widely used in the traditional SPS-HT. Moreover, each Hadamard coefficient is coded along the time dimension with a different sequency value such that the alternating current (AC) measurements of the time-domain signal can be used to reconstruct all Hadamard coefficients simultaneously, which reduces the influence of noise and dramatically speeds up data acquisition.
View Article and Find Full Text PDFBackground The burden of psychiatric illness following a head injury may have implications on the disease prognosis. The present study evaluated the association of depression and anxiety with traumatic brain injury (TBI). Methods A case-control study was conducted in Karachi, Pakistan, from 2nd July 2021 and 30th January 2022, including individuals of age 18 and above of both genders, with or without a mild head trauma history, forming the case and control groups, respectively.
View Article and Find Full Text PDFThe purpose of the research is to predict the compressive and flexural strengths of the concrete mix by using waste marble powder as a partial replacement of cement and sand, based on the experimental data that was acquired from the laboratory tests. In order to accomplish the goal, the models of Support vector machines, Support vector machines with bagging and Stochastic, Linear regression, and Gaussian processes were applied to the experimental data for predicting the compressive and flexural strength of concrete. The effectiveness of models was also evaluated by using statistical criteria.
View Article and Find Full Text PDFIntroduction: The effects of the COVID-19 pandemic on mental health have been profound. Mental health and diabetes self-care are inter-related. We examined whether COVID-19 anxiety, depressive symptoms and health anxiety were associated with domains of diabetes self-management and investigated whether greater COVID-19 anxiety syndrome would independently contribute to suboptimal diabetes self-care.
View Article and Find Full Text PDFHypertensive crises is still a major public health problem, causing end organ damage like myocardial infarction, stroke, and renal failure. Labetalol and nitroglycerine are among the two most commonly used medicine to control the blood pressure, but there is no head to head comparison between these two medicines. This was a prospective randomized non-blinded study which included 50 patients of hypertensive crises, out which 25 patients received intravenous labetalol and 25 patients received intravenous nitroglycerine.
View Article and Find Full Text PDFConcrete is a composite material that is commonly used in the construction industry. It will certainly be exposed to fires of varying intensities when used in buildings and industries. The major goal of this article was to look into the influence of mineral additions such as foundry sand and marble dust on the residual characteristics of concrete.
View Article and Find Full Text PDFIn recent times, tremendous efforts have been devoted to the efficient and cost-effective advancements of electrochemically active metal oxide nanomaterials. Here, we have synthesized a facile nanomaterial of ZnO@PdO/Pd by employing extracted fuel from leaves following a hydrothermal route. The phyto-fueled ZnO@PdO/Pd nanomaterial was fabricated into a supercapacitor electrode and was scrutinized by galvanostatic charge-discharge, electrochemical impedance spectroscopy and cyclic voltammetry to evaluate its energy storage potential, and transport of electrons and conductivity.
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