Publications by authors named "Maliha Kabir"
Article Synopsis
- Captopril, widely used to treat various cardiovascular conditions, shows potential for bladder cancer patients with hypertension due to its interaction with relevant proteins associated with the disease.* -
- The study identified key protein targets of captopril using Bioinformatics tools, revealing that it effectively inhibits overexpressed genes like MMP9 and LCN2, which are linked to poor survival rates in bladder cancer.* -
- The research suggests further laboratory studies are needed to validate captopril's effectiveness in treating bladder cancer, highlighting its dual role in managing both hypertension and cancer-related complications.*
MicroRNA in Fibrotic Disorders: A Potential Target for Future Therapeutics.
Front Biosci (Landmark Ed)
November 2023
Fibrotic disorders are defined by accumulating excessive extracellular matrix (ECM) components, especially collagens, in various organs, leading to tissue scarring and organ dysfunction. These conditions are associated with significant challenges in the healthcare system because of their progressive nature and limited treatment options. MicroRNAs (miRNAs) are small non-coding RNA molecules (approximately 22 nucleotides) that modulate gene expression by selectively targeting mRNAs for degradation or translational repression.
View Article and Find Full Text PDFIncreasing human population, deforestation and man-made climate change are likely to exacerbate the negative effects on freshwater ecosystems and species endangerment. Consequently, the biodiversity of freshwater continues to dwindle at an alarming rate. However, this particular topic lacks sufficient attention from conservation ecologists and policymakers, resulting in a dearth of data and comprehensive reviews on freshwater biodiversity, specifically.
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