[TNF-α and soluble receptor TNF-α type 1 in children with diabetes mellitus type 1].

Introduction: TNF-α, and its soluble form sTNFR1, as proinflammatory hormone plays a great role in pathogenesis of auto immunological diseases, insulin resistance, both carbohydrates and fat metabolism and development of late complications in type 1 diabetes mellitus (DMT1) patients.

Aim Of The Study: To asses TNF-α and sTNFR1 levels in children with DMT1 and to analyze the correlation with anthropometric parameters, metabolic control and the influence of the kind of insulin therapy.

Material And Methods: 67 patients, aged from 3.

[Leptin and soluble leptin receptor in children with type 1 diabetes mellitus].

Introduction: Leptin and soluble form of leptin receptor play a great role in both carbohydrate and fat metabolism which is very important in diabetes mellitus type (DMT1) patients.

Aim Of The Study: To asses leptin and soluble leptin receptor levels in children with DMT1 and to analyze correlation with anthropometric parameters, metabolic control and the influence of various kinds of insulin therapy.

Material And Methods: 67 patients, aged from 3.