The Influence of FTO Polymorphism rs9939609 on Obesity, Some Clinical Features, and Disturbance of Carbohydrate Metabolism in Patients with Psoriasis.

Background: Psoriasis is often accompanied by obesity, hyperlipidemia, diabetes, and metabolic syndrome as risk factors of cardiovascular conditions and premature mortality.

Objective: The study was aimed at investigating whether psoriatic patients, who carry risk allele of obesity-related gene, are more predisposed to obesity and metabolic disturbances and whether it influences the severity of psoriasis.

Methods: 197 patients with psoriasis, representing Lower Silesia region of Poland, underwent physical examination and anthropometric measurements.