Publications by authors named "Malgorzata Scios"
Int J Mol Sci
October 2024
Article Synopsis
- Alzheimer's disease (AD) is the most common dementia, and its exact causes are still unclear, with major hypotheses focusing on cholinergic, beta-amyloid, and Tau proteins, while newer research looks into immunological factors and proteins like alpha-synuclein and TDP-43.
- Recent studies highlight tunneling nanotubes (TNTs) as crucial for the spread of harmful proteins in the brains of AD patients; these structures can link non-adjacent cells and may transport proteins like Aβ and Tau between them.
- Current treatments for AD mainly address symptoms and have shown limited success with Aβ-targeting drugs, making the study of TNTs essential for understanding the disease better and finding new therapies.
