Publications by authors named "Malgorzata Plen"
Article Synopsis
- Pakistan is among the top countries in the world for tuberculosis (TB) and drug-resistant TB, yet there's a lack of genetic data on the strains present in the country.
- A study analyzed the genetic diversity of multidrug-resistant TB (MDR-TB) isolates from Punjab, finding 53 different spoligotypes and identifying several prevalent sublineages such as CAS1_DELHI, T1, and Beijing.
- The research indicated that about a third of the MDR-TB cases are clustered, suggesting moderate levels of active transmission within the region.
Pakistan ranks 5th among the world's highest tuberculosis (TB) burden countries alongside the 6th among countries with the highest burden of drug-resistant TB, including multi-drug resistant (MDR)-TB. Methods for rapid and reliable drug susceptibility testing (DST) are prerequisite for the prompt institution of effective anti-TB treatment. The aim of this study was to evaluate the efficiency of Genotype MTBDR and MTBDR assays for the detection of MDR and (pre-) extensively drug-resistant (XDR-TB) isolates in Pakistan.
View Article and Find Full Text PDFAim: To investigate the in vitro activity of silver NPs (AgNPs) against pathogenic microalgae of the Prototheca genus.
Materials & Methods: The antialgal potential of AgNPs against Prototheca species of both clinical and environmental origin was assessed from minimum inhibitory (algistatic) and algicidal concentrations. The in vitro cytotoxicity of AgNPs against bovine mammary epithelial cell line was evaluated by means of the standard MTT assay.