Clinical evidence of caries prevention by hydroxyapatite: An updated systematic review and meta-analysis.

Objectives: A systematic review and meta-analysis were undertaken to update our 3-year-old meta-analysis to include RCTs, in vivo, and in situ clinical evidence that showed hydroxyapatite in oral care products can reduce dental caries.

Data: Using the PICO guide, published clinical trials were searched where subjects (P) of all ages, with primary, mixed or permanent dentitions, using toothpastes, mouthwashes or gels containing hydroxyapatite as an active ingredient (I) were compared to subjects who used placebo or no intervention, or fluoride-containing positive controls (C), and the outcomes (O) were direct measurement of reduced dental caries or suitable proxy for reduced caries risk.

Sources: PubMed, Scopus, EMBASE, and Web of Science databases were searched using search terms from previous searches.

Diet Traps during Eating Disorders among Dentate Patients at an Oral Health Glance.

Persons suffering from eating disorders (ED) may often experience a recurrence/persistence symptoms despite the completion of psychiatric therapy. In most cases, their general health status is linked to current nutritional behaviors. Medical professionals, general practitioners (GPs), dieticians, and dentists may see those patients in their practices.

Caries-preventing effect of a hydroxyapatite-toothpaste in adults: a 18-month double-blinded randomized clinical trial.

Background: Dental caries is a worldwide challenge for public health. The aim of this 18-month double-blinded, randomized, clinical trial was to compare the caries-preventing effect of a fluoride-free, hydroxyapatite toothpaste (test) and a toothpaste with sodium fluoride (1450 ppm fluoride; positive control) in adults.

Methods: The primary endpoint was the percentage of subjects showing no increase in overall Decayed Missing Filled Surfaces (DMFS) index.

Dental Status and Oral Health Behaviors of Selected 45-74-Year-Old Men from Northeastern Poland.

The aim of this study was to assess the dental status and oral health behaviors of selected 45-74-year-old men from northeastern Poland. A total of 419 men were included. A questionnaire on demographic data, socioeconomic status and oral health behaviors was conducted.

Management for Caries Prevention in ADHD Children.

Emotional Dysregulations (ED) represent a major health risk present in about 5% of children and are associated with diverse forms of childhood psychiatric disorders and symptoms such as Attention-Deficit/Hyperactivity Disorder (ADHD) [...

Cytotoxicity and Oxidative Stress Induction by Root Canal Sealers in Human Periodontal Ligament Fibroblasts: An in vitro Study.

Introduction: The aim of the study was to investigate the cytotoxicity, the profile of cell death, and the level of oxidative stress in human periodontal ligament fibroblasts (HPdLFs) after exposure to selected root canal sealers.

Methods And Materials: Freshly mixed or set Endomethasone N (EN), RealSeal (RSEAL), Roeko Seal Automix (RSA), and Sealapex (SP) were incubated with HPdLFs. Fluorescein isothiocyanate (FITC)-annexin V (AnV) and propidium iodide (PI) staining followed by flow cytometry was used to identify the effects of the materials on cell viability and the profile of cell death.

Impact of a toothpaste with microcrystalline hydroxyapatite on the occurrence of early childhood caries: a 1-year randomized clinical trial.

The aim of this trial was to determine whether a toothpaste with microcrystalline hydroxyapatite is not inferior to a fluoride toothpaste in prevention of caries in children. This double-blinded randomized control trial compared two toothpastes regarding the occurrence of caries lesions using International Caries Detection and Assessment System (ICDAS) ≥ code 1 on the primary dentition within 336 days. The test group used a fluoride-free hydroxyapatite toothpaste three times daily while control group used a toothpaste with fluoride.

Comparison of the radiopacity of selected materials used for vital pulp therapy: An in vitro assessment.

Background: An assessment of the therapeutic effects of vital pulp treatment is based on both clinical and radiological evaluation.

Objectives: The aim of the research was a long-term (after 1, 2, 4, 6, and 8 weeks) radiological assessment of X-ray absorption by 8 selected materials used for the vital treatment of dental pulp.

Material And Methods: The materials, prepared in accordance with the manufacturers' recommendations, were placed in molds measuring 10 mm in diameter and 2 mm in thickness.

A comparative assessment of the antibacterial activity of root canal sealers on 2 Actinomyces species: An in vitro study.

Background: Actinomyces species have a low virulence and pathogenicity, but under specific circumstances they may be involved in root canal and periapical tissue infections.

Objectives: The aim of the study was to investigate the antibacterial activity of various root canal sealers on standardized strains of Actinomyces.

Material And Methods: The materials tested in this study included AH Plus™ Jet (AH), Apexit® Plus (AP), Endomethasone N (EN), GuttaFlow® (GF), Hybrid Root SEAL (HB), MTA Fillapex (FL), Real® Seal (RCS), Roeko Seal Automix (RSA), Sealapex™ (SP), and Tubli-Seal™ (TS).

Effect of root canal sealers on human periodontal ligament fibroblast viability: ex vivo study.

The aim of the study was to compare ex vivo the toxic effects of six root canal sealers immediately after mixing or setting on human periodontal ligament fibroblasts (HPdLF). Freshly mixed (I group) or set (allowed to dry for 24 h) (II group) specimens of AH Plus Jet (AH), Apexit Plus (AP), MTA Fillapex (FL), GuttaFlow (GF), MetaSEAL Soft (META), and Tubli-Seal (TS) were prepared. HPdLF were exposed for 24 h to the specimens.

Evaluation of the cytotoxicity of selected conventional glass ionomer cements on human gingival fibroblasts.

Background: Dentistry materials are the most frequently used substitutes of human tissues. Therefore, an assessment of dental filling materials should cover not only their chemical, physical, and mechanical characteristics, but also their cytotoxicity.

Objectives: To compare the cytotoxic effects of 13 conventional glass ionomer cements on human gingival fibroblasts.

Direct Pulp Capping in Primary Molars using Mineral Trioxide Aggregate: An in Vivo Study.

Objective: To do a clinical and radiographic evaluation of the effectiveness of MTA when used as a direct pulp capping material in primary molars.

Study Design: Clinical and radiographic follow-up was performed on 30 primary molars with deep caries lesions in 30 patients from 3 to 9.75 years of age.

A laboratory study evaluating the pH of various modern root canal filling materials.

Background: Alkaline pH is responsible for antibacterial activity and the stimulation of periapical tissue healing. It neutralizes the acidic environment of inflammatory tissues in the periapical region of the teeth and favors bone repair by activating tissue enzymes.

Objectives: The aim of this study was to evaluate and compare in vitro the pH of 8 root canal filling materials (sealers and points) -AH Plus Jet (AH), Apexit Plus (AP), Endomethasone N (END), Epiphany (EP), GuttaFlow (GF), gutta-percha (G), Resilon (R), Tubliseal (T).

Evaluation of cytotoxicity and pH changes generated by various dental pulp capping materials - an in vitro study.

Introduction: Various materials are used in direct dental pulp capping method. Their biocompatibility and alkalizing abilities are of primary importance affecting therapeutic effects. The aim of this study was to evaluate and compare the cytotoxicity of various pulp-capping materials on human gingival fibroblasts and investigate the pH changes induced by these materials.

Assessment of cytotoxic potential of root canal sealers after hardening - an ex vivo study.

Aim: The aim of this study was to perform a comparative assessment of the toxic action of root canal sealers currently on the market on human gingival fibroblasts after setting.

Material/methods: The inserts with an equal quantity of set root canal sealers were transferred into 24-well culture dishes containing human gingival fibroblasts cultured in Dulbecco's Modified Eagle's Medium (DMEM) supplemented with 10% fetal calf serum (FCS). The dishes with materials were incubated at 37°C, 100% humidity and in an atmosphere of 5% CO2 for 24 h.

A microcomputed tomography-based comparison of root canal filling quality following different instrumentation and obturation techniques.

Objective: With a microcomputed tomography (microCT) imaging device, we aimed to quantitatively evaluate root canal fillings after commonly used endodontic procedures and also tested the suitability of microCT for this purpose.

Materials And Methods: Eighty single roots were instrumented and obturated with gutta-percha and Tubli-Seal. They were divided into 4 groups of 20.

Antibacterial activity of selected glass ionomer cements.

Introduction: The aim of the paper was to determine the antibacterial activity of four glass ionomer cements against bacteria of the genera Streptococcus and Lactobacillus.

Material And Methods: Four capsulated glass ionomer cements were applied in the study: Fuji Triage (GC), Fuji IX (GC), Ketac Molar (3M Espe) and Ketac Silver (3M Espe). Four standard bacterial strains were used to assess the antibacterial activity of the studied cements: Streptococcus mutans, S.

Antibacterial activity of two Mineral Trioxide Aggregate materials in vitro evaluation.

Introduction: It has been documented that total removal of carious dentin, assessed according to clinical criteria, does not mean complete eradication of bacteria. For that reason in prevention of caries and pulp inflammations, application of the materials having high antibacterial properties seems to be indispensable.

Aim: Determination of antibacterial activities of two white Mineral Trioxide Aggregate (MTA) preparations against bacteria of the genus Streptococcus.

Endodontic treatment of complicated traumatic deciduous teeth damage--a case report.

The 11-year-old boy was diagnosed with severe external root resorption of the tooth 11 and chronic exacerbated apical periodontitis of the tooth 12. Additionally, the tooth 12 showed signs of dilaceration. The history revealed that at the age of 5, the boy had dislocated his maxillary deciduous incisors with impaction to the tissues.