Disruptions within gut microbiota composition induced by improper antibiotics therapy as a probable trigger factor for development of depression - Case Reports.

A growing body of evidence confirms that immune activation and low-grade inflammation could be defined as risks factors for the development and progression of mood episodes. A suggested mechanism leading to immune-inflammatory imbalance is the change in gut microbiota composition provoked by intestinal permeability. Three cases of patients with first episode of depression: a 30-year-old man and two 41 and 46-year-old women are presented in the study.