Publications by authors named "Malgorzata Belczyk"
Article Synopsis
- This study explored how atorvastatin affects muscle protein synthesis and degradation through specific pathways, specifically looking at muscle fiber types.
- Rats were given atorvastatin, and various muscle tissues were analyzed for changes in specific protein levels and gene expressions related to muscle health.
- Results showed varying impacts of atorvastatin on different muscle types, with no significant muscle damage, suggesting that atorvastatin's effects on muscle may differ based on muscle fiber characteristics.
5-fluorouracil (5-FU), which is a commonly used chemotherapy agent exerts undesired cardiac toxicity. Mitochondrial dysfunction is thought to be one of potentially important mechanisms of 5-FU- induced cardiotoxicity. α-ketoglutarate dehydrogenase (α-KGDHC) is the key regulatory enzyme of TCA cycle.
View Article and Find Full Text PDFWhite adipose tissue plays an important role in the catabolism of branched chain amino acids (BCAAs). Two initial regulatory steps in BCAAs catabolism are catalyzed by branched chain aminotransferase (BCAT) and branched chain α-keto acid dehydrogenase complex (BCKDH complex), respectively. It has been demonstrated that synthetic ligands for PPARγ receptors increased mRNA levels for enzymes involved in BCAAs catabolism.
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