Publications by authors named "Malene Risager Lykke"

Background: Evidence of an association between trigeminal neuralgia (TN) and subsequent cancer risk remains sparse. The present study aimed to examine the association between TN and cancer risk in the Danish population.

Methods: A nationwide population-based cohort study using hospital diagnoses collected routinely and prospectively from Danish population-based registries in 1994-2022.

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Importance: The risk of epilepsy after neonatal invasive Group B Streptococcus (iGBS) disease, particularly iGBS sepsis, is poorly understood.

Objective: To examine the association between neonatal iGBS (sepsis or meningitis) and long-term risk of epilepsy, stratified by sex, prematurity, and maternal socioeconomic position (SEP).

Design, Setting, And Participants: This population-based cohort study was conducted in Denmark with an inclusion period from 1997 through 2017 and follow-up until the end of 2018.

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Introduction: Healthy women of reproductive age have a vaginal pH around 4.5, whereas little is known about pH in the upper genital tract. A shift in the vaginal microbiota may result in an elevated pH in the upper genital tract.

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Objective: The aim of this study was to evaluate the effect of fluorescence cystoscopy and immediate post-transurethral resection of the bladder (TURB) chemoprophylaxis on the risk of recurrence of non-muscle-invasive bladder cancer (NMIBC) under routine clinical conditions.

Materials And Methods: Fluorescence cystoscopy using hexyl-aminolevulinate and post-TURB chemoprophylaxis using mitomycin C were simultaneously introduced in an effort to reduce the recurrence of NMIBC. In total, 190 consecutive patients were enrolled over a 2 year period and followed as the intervention group; 216 patients treated over a 2 year period before introduction served as controls.

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Synopsis of recent research by authors named "Malene Risager Lykke"

  • - Malene Risager Lykke's recent research primarily focuses on the long-term health implications of invasive infectious diseases in neonates, specifically investigating the correlation between neonatal invasive Group B Streptococcus disease and the risk of developing epilepsy in later life.
  • - Her studies also explore the effects of vaginal microbiota on vaginal and upper genital tract pH levels, contributing to the understanding of women's reproductive health and the potential implications for abnormal microbiota conditions.
  • - Additionally, Lykke has investigated innovative approaches to reducing recurrence rates in non-muscle-invasive bladder cancer through the use of photodynamic diagnosis and chemoprophylaxis administered after transurethral resection, enhancing treatment protocols in clinical practice.