Emergence of hypermucoviscous colistin-resistant high-risk convergent ST-2096 clone from Pakistan.

convergent clones are considered a threat to healthcare settings. Here we report a comprehensive genomic profiling of an emerging colistin-resistant ST-2096 convergent clone from Pakistan. Whole-genome sequencing was performed and raw reads were assembled antimicrobial resistance and virulence genes were predicted using various online tools.

Elucidation of molecular mechanism for colistin resistance among Gram-negative isolates from tertiary care hospitals.

Unlabelled: Antimicrobial resistance is a growing concern of global public health. The emergence of colistin-resistance among carbapenem-resistant (CPR) Gram-negative bacteria causing fear of pan-resistance, treatment failure, and high mortality across the globe.

Aim: To determine the genotypic colistin-resistance mechanisms among colistin-resistant (CR)Gram-negative clinical isolates along with genomic insight into hypermucoviscous(hv)-CR-Klebsiella pneumoniae.