Meteorological factors, population immunity, and COVID-19 incidence: A global multi-city analysis.

Objectives: While COVID-19 continues to challenge the world, meteorological variables are thought to impact COVID-19 transmission. Previous studies showed evidence of negative associations between high temperature and absolute humidity on COVID-19 transmission. Our research aims to fill the knowledge gap on the modifying effect of vaccination rates and strains on the weather-COVID-19 association.

Impacts of land-use and land-cover changes on temperature-related mortality.

Background: Land-use and land-cover change (LULCC) can substantially affect climate through biogeochemical and biogeophysical effects. Here, we examine the future temperature-mortality impact for two contrasting LULCC scenarios in a background climate of low greenhouse gas concentrations. The first LULCC scenario implies a globally sustainable land use and socioeconomic development (sustainability).

Long-term Associations Between Time-varying Exposure to Ambient PM 2.5 and Mortality: An Analysis of the UK Biobank.

Background: Evidence for long-term mortality risks of PM 2.5 comes mostly from large administrative studies with incomplete individual information and limited exposure definitions. Here we assess PM 2.

Association between long-term exposure to low ambient PM and cardiovascular hospital admissions: A UK Biobank study.

Introduction: A causal link between air pollution exposure and cardiovascular events has been suggested. However fewer studies have investigated the shape of the associations at low levels of air pollution and identified the most important temporal window of exposure. Here we assessed long-term associations between particulate matter < 2.

Temperature-related mortality burden and projected change in 1368 European regions: a modelling study.

Background: Excessively high and low temperatures substantially affect human health. Climate change is expected to exacerbate heat-related morbidity and mortality, presenting unprecedented challenges to public health systems. Since localised assessments of temperature-related mortality risk are essential to formulate effective public health responses and adaptation strategies, we aimed to estimate the current and future temperature-related mortality risk under four climate change scenarios across all European regions.

High resolution mapping of nitrogen dioxide and particulate matter in Great Britain (2003-2021) with multi-stage data reconstruction and ensemble machine learning methods.

In this contribution, we applied a multi-stage machine learning (ML) framework to map daily values of nitrogen dioxide (NO) and particulate matter (PM and PM) at a 1 km resolution over Great Britain for the period 2003-2021. The process combined ground monitoring observations, satellite-derived products, climate reanalyses and chemical transport model datasets, and traffic and land-use data. Each feature was harmonized to 1 km resolution and extracted at monitoring sites.

Real-time forecast of temperature-related excess mortality at small-area level: towards an operational framework.

The development of innovative tools for real-time monitoring and forecasting of environmental health impacts is central to effective public health interventions and resource allocation strategies. Though a need for such generic tools has been previously echoed by public health planners and regional authorities responsible for issuing anticipatory alerts, a comprehensive, robust and scalable real-time system for predicting temperature-related excess deaths at a local scale has not been developed yet. Filling this gap, we propose a flexible operational framework for coupling publicly available weather forecasts with temperature-mortality risk functions specific to small census-based zones, the latter derived using state-of-the-art environmental epidemiological models.

Ambient heat exposure and kidney function in patients with chronic kidney disease: a post-hoc analysis of the DAPA-CKD trial.

Background: Higher temperatures are associated with higher rates of hospital admissions for nephrolithiasis and acute kidney injury. Occupational heat stress is also a risk factor for kidney dysfunction in resource-poor settings. It is unclear whether ambient heat exposure is associated with loss of kidney function in patients with established chronic kidney disease.

A better integration of health and economic impact assessments of climate change.

Climate change could lead to high economic burden for individuals (i.e. low income and high prices).

Impact of population aging on future temperature-related mortality at different global warming levels.

Older adults are generally amongst the most vulnerable to heat and cold. While temperature-related health impacts are projected to increase with global warming, the influence of population aging on these trends remains unclear. Here we show that at 1.

SHARE-ENV: A Data Set to Advance Our Knowledge of the Environment-Wellbeing Relationship.

Climate change interacts with other environmental stressors and vulnerability factors. Some places and, owing to socioeconomic conditions, some people, are far more at risk. The data behind current assessments of the environment-wellbeing nexus is coarse and regionally aggregated, when considering multiple regions/groups; or, when granular, comes from ad hoc samples with few variables.

Seasonality of mortality under climate change: a multicountry projection study.

Background: Climate change can directly impact temperature-related excess deaths and might subsequently change the seasonal variation in mortality. In this study, we aimed to provide a systematic and comprehensive assessment of potential future changes in the seasonal variation, or seasonality, of mortality across different climate zones.

Methods: In this modelling study, we collected daily time series of mean temperature and mortality (all causes or non-external causes only) via the Multi-Country Multi-City Collaborative (MCC) Research Network.

Reconstructing individual-level exposures in cohort analyses of environmental risks: an example with the UK Biobank.

Recent developments in linkage procedures and exposure modelling offer great prospects for cohort analyses on the health risks of environmental factors. However, assigning individual-level exposures to large population-based cohorts poses methodological and practical problems. In this contribution, we illustrate a linkage framework to reconstruct environmental exposures for individual-level epidemiological analyses, discussing methodological and practical issues such as residential mobility and privacy concerns.

Optimal heat stress metric for modelling heat-related mortality varies from country to country.

Combined heat and humidity is frequently described as the main driver of human heat-related mortality, more so than dry-bulb temperature alone. While based on physiological thinking, this assumption has not been robustly supported by epidemiological evidence. By performing the first systematic comparison of eight heat stress metrics (i.

Neglected implications of land-use and land-cover changes on the climate-health nexus.

Climate change can substantially affect temperature-related mortality and morbidity, especially under high green-house gas emission pathways. Achieving the Paris Agreement goals require not only drastic reductions in fossil fuel-based emissions but also land-use and land-cover changes (LULCC), such as reforestation and afforestation. LULCC has been mainly analysed in the context of land-based mitigation and food security.

Importance of humidity for characterization and communication of dangerous heatwave conditions.

Heatwaves are one of the leading causes of climate-induced mortality. Using the examples of recent heatwaves in Europe, the United States and Asia, we illustrate how the communication of dangerous conditions based on temperature maps alone can lead to insufficient societal perception of health risks. Comparison of maximum daily values of temperature with physiological heat stress indices accounting for impacts of both temperature and humidity, illustrates substantial differences in geographical extent and timing of their respective peak values during these recent events.

Excess mortality attributed to heat and cold: a health impact assessment study in 854 cities in Europe.

Background: Heat and cold are established environmental risk factors for human health. However, mapping the related health burden is a difficult task due to the complexity of the associations and the differences in vulnerability and demographic distributions. In this study, we did a comprehensive mortality impact assessment due to heat and cold in European urban areas, considering geographical differences and age-specific risks.

Increased energy use for adaptation significantly impacts mitigation pathways.

Climate adaptation actions can be energy-intensive, but how adaptation feeds back into the energy system and the environment is absent in nearly all up-to-date energy scenarios. Here we quantify the impacts of adaptation actions entailing direct changes in final energy use on energy investments and costs, greenhouse gas emissions, and air pollution. We find that energy needs for adaptation increase considerably over time and with warming.

Small-area assessment of temperature-related mortality risks in England and Wales: a case time series analysis.

Background: Epidemiological literature on the health risks associated with non-optimal temperature has mostly reported average estimates across large areas or specific population groups. However, the heterogeneous distribution of drivers of vulnerability can result in local differences in health risks associated with heat and cold. We aimed to analyse the association between ambient air temperature and all-cause mortality across England and Wales and characterise small scale patterns in temperature-related mortality risks and impacts.

Comparison of weather station and climate reanalysis data for modelling temperature-related mortality.

Epidemiological analyses of health risks associated with non-optimal temperature are traditionally based on ground observations from weather stations that offer limited spatial and temporal coverage. Climate reanalysis represents an alternative option that provide complete spatio-temporal exposure coverage, and yet are to be systematically explored for their suitability in assessing temperature-related health risks at a global scale. Here we provide the first comprehensive analysis over multiple regions to assess the suitability of the most recent generation of reanalysis datasets for health impact assessments and evaluate their comparative performance against traditional station-based data.

Air-conditioning and the adaptation cooling deficit in emerging economies.

Increasing temperatures will make space cooling a necessity for maintain comfort and protecting human health, and rising income levels will allow more people to purchase and run air conditioners. Here we show that, in Brazil, India, Indonesia, and Mexico income and humidity-adjusted temperature are common determinants for adopting air-conditioning, but their relative contribution varies in relation to household characteristics. Adoption rates are higher among households living in higher quality dwellings in urban areas, and among those with higher levels of education.