Publications by authors named "Malavasi Mario"

Background: Monitoring respiratory rate (RR) is recommended at the time of hospital presentation for acute decompensation in heart failure (HF). Device-based continuous monitoring of RR may be helpful for diagnostic and prognostic stratification after implantable cardioverter-defibrillator (ICD) implantation. This study was undertaken to analyze short- and long-term changes in ICD-measured RR and to relate RR with the patient's clinical status and the occurrence of HF events.

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Aims: Control of atrioventricular (AV) node conduction by means of high-frequency stimulation (HFS) of efferent AV node vagal stimulation (AVNS) fibres enables the ventricular rate (VR) to be modulated during atrial fibrillation (AF). The aims of this study were to verify, on 18-month follow-up, the reproducibility of the dromotropic effect obtained on implantation and the long-term reliability of the system in patients who received an implantable cardioverter-defibrillator (ICD) with a standard atrial lead positioned at a location suitable for AVNS.

Methods And Results: We enrolled 12 patients with paroxysmal or persistent AF who were candidates for ICD.

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Aims: The aims of the study were to evaluate the 24-h beat-to-beat heart rate (RR) and blood pressure changes during closed loop stimulation (DDD-CLS) pacing and conventional fixed rate DDD pacing with respect to spontaneous activity.

Methods: We simultaneously and continuously measured beat-to-beat heart rate and blood pressure for 24 h in patients implanted with Inos2+ (Biotronik GmbH, Berlin, Germany). A randomised cross-over comparison of DDD-CLS and DDD pacing was performed by short- and long-term analyses.

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Article Synopsis
  • This study investigated how L-arginine and vitamin C affect respiratory variability in patients with chronic heart failure.
  • It was found that healthy individuals can effectively regulate blood vessel resistance via nitric oxide produced by the endothelium.
  • In contrast, patients with chronic heart failure lack this ability, indicating a significant difference in vascular regulation between healthy individuals and those with heart conditions.
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