Horse Herd Optimization with Gate Recurrent Unit for an Automatic Classification of Different Facial Skin Disease.

The human body's largest organ is the skin which covers the entire body. The facial skin is one area of the body that needs careful handling. It can cause several facial skin diseases like acne, eczema, moles, melanoma, rosacea, and many other fungal infections.

Tuning the physiochemical properties of polycaprolactone-hydroxyapatite composite films by gamma irradiation for biomedical applications.

Physiochemical properties of polycaprolactone-hydroxyapatite (PCL-HAp) composites were investigated in the pristine and after irradiation of γ rays (25, 50, 75, and 100 kGy). PCL-HAp composites were synthesized by solvent evaporation and characterized using spectroscopic methods as well as biological assays. The surface roughness (RMS) of the irradiated composite film (at 75 kGy) was 80 times higher than that of the pristine.

Alternate management of an anterior maxillary dentigerous cyst in a paediatric patient.

The purpose of this article is to show alternate management of an anterior maxillary dentigerous cyst in a paediatric patient. An 8-year-old male child reported to the Department of Oral and Maxillofacial surgery with the chief complaint of swelling in the upper left side of the face for 2 months. Based on the clinical and radiological findings of cystic cavity along with impacted tooth, lesion was diagnosed as dentigerous cyst and surgical enucleation was planned under general anaesthesia.

Disposable biosensors based on metal nanoparticles.

The coronavirus disease2019 (COVID-19) pandemic has highlighted the need for disposable biosensors that can detect viruses in infected patients quickly due to fast response and also at a low cost.The present review provides an overview of the applications of disposable biosensors based on metal nanoparticles in enzymatic and non-enzymatic sensors with special reference to glucose and HO, immunosensors as well as genosensors (DNA biosensors in which the recognized event consists of the hybridization reaction)for point-of-care diagnostics. The disposable biosensors for COVID19 have also been discussed.

Calcifying Epithelial Odontogenic Cyst of Maxilla: A Clinical and Histological Rarity with Literature Review.

A cyst is defined as a pathological cavity which may or may not have an epithelial lining and which has a fluid, semi-fluid, or gaseous contents and is not formed by the accumulation of pus. The calcifying epithelial odontogenic cyst (CEOC) was first reported by Gorlin et al. in 1962.

Prevalence of gastrointestinal helminth parasites in domestic ruminants from Srikakulam district, Andhra Pradesh, India.

Coprological studies on the prevalence of gastrointestinal helminth (GI) parasites in domestic ruminants from Srikakulam district of Andhra Pradesh, India, were carried out for a period of one year from January 2019 to December 2019. Fecal examination was done using direct smear, sedimentation and floatation methods. Altogether 3527 fecal samples were examined including 595 from cows, 485 from buffaloes, 1342 from sheep and 1105 from goat.

CD4 Cell Counts, Lipid Profile, and Oral Manifestations in HIV-Infected and AIDS Patients.

Objectives: The present study aimed to evaluate CD4 cell counts, lipid profile, and oral manifestations in human immunodeficiency virus (HIV)-infected and acquired immune deficiency syndrome (AIDS) patients and their correlation with seronegative controls.

Materials And Methods: In this cross-sectional, hospital-based study, there were three groups of subjects: group A consisting of 500 healthy patients (controls), group B composed of 500 HIV-infected patients, and group C comprised of 500 AIDS patients based on their CD4 cell counts. CD4 cell counts were assessed using the CyFlow counter.

Active Volume Control in Smart Phones Based on User Activity and Ambient Noise.

To communicate efficiently with a prospective user, auditory interfaces are employed in mobile communication devices. Diverse sounds in different volumes are used to alert the user in various devices such as mobile phones, modern laptops and domestic appliances. These alert noises behave erroneously in dynamic noise environments, leading to major annoyances to the user.

Fabrication of nanopatterned PLGA films of curcumin and TPGS for skin cancer.

Squamous cell carcinoma treatment has limited therapeutic options and the incidence rate is increasing recently. In the present investigation, we developed poly(lactic-co-glycolic acid) (PLGA) nanopatterned films (NPFs) through poly dimethyl siloxane (PDMS) cast molding technique and explored its therapeutic efficacy in combination with curcumin and tocopherol poly (ethylene glycol) 1000 succinate (TPGS). Herein, we demonstrate the preparation and characterization of curcumin loaded tocopherol polyethylene glycol 1000 succinate stabilized poly (lactic-co-glycolic) acid nanopatterned films (CTP-NPFs).

Green synthesis and characterization of bioinspired silver, gold and platinum nanoparticles and evaluation of their synergistic antibacterial activity after combining with different classes of antibiotics.

A facile one step green synthesis of silver (AgNP), gold (AuNP) and platinum (PtNP) nanoparticles has been attempted using the rind extract of the fruit of Garcinia mangostana L. The rind of the fruit is enriched with wide varieties of natural resources which could be conveniently exploited as alternative for synthesis of nanoparticles eliminating the need for hazardous chemical methods. The formation of gold nanoparticles occurred at room temperature within a few seconds while the formation of silver and platinum nanoparticles was obtained after heating the solution for 20 min at 80 °C.

Hydrophilic poly (ethylene glycol) capped poly (lactic-co-glycolic) acid nanoparticles for subcutaneous delivery of insulin in diabetic rats.

The aim of the present study is to evaluate the effect of insulin loaded poly(ethylene glycol) capped poly(lactic-co-glycolic)acid nanoparticles (ISPPLG NPs) by subcutaneous administration in diabetic rats. A series of biodegradable low molecular weight PLGA [90/10 (PLG2) and 80/20 (PLG4)] copolymers were synthesized by melt polycondensation and their ISPPLG NPs were synthesized by water-oil-water (W/O/W) emulsion solvent evaporation method. The PLGA copolymers and their nanoparticles were characterized.

Novel PLGA-based nanoparticles for the oral delivery of insulin.

Background: Insulin is the drug therapy for patients with insulin-dependent diabetes mellitus. A number of attempts have been made in the past to overcome the problems associated with the oral delivery of insulin, but with little success. Orally administered insulin has encountered with many difficulties such as rapid degradation and poor intestinal absorption.

One pot green synthesis of Ag, Au and Au-Ag alloy nanoparticles using isonicotinic acid hydrazide and starch.

Gold-silver alloy nanoparticles were synthesized via chemical reduction of varying mole fractions of chloroauric acid (HAuCl4) and silver nitrate (AgNO3) by environmentally benign isonicotinic acid hydrazide (INH) in the presence of starch as a capping agent in aqueous medium. The absorption spectra of Au-Ag nanoparticles show blue shift with increasing silver content indicating the formation of alloy nanoparticles. When the Ag content in the alloy decreases the size of the nanoparticles increases and as a result of which the oxidation potential also increases.

Dental prosthetic status and prosthetic needs of the institutionalized elderly living in geriatric homes in Hyderabad: a pilot study.

Introduction: To promote oral health among the elderly, we need to know their prosthetic status and prosthetic need. Hence, a survey of prosthetic status and need of elderly inmates of geriatric homes in Hyderabad was done.

Materials And Methods: A cross-sectional study was undertaken, and 174 subjects aged 60 years and above were examined of which 103 were male and 71 were female (59.

Synthesis of biodegradable polymeric nanoparticles and their controlled drug delivery for tuberculosis.

Tuberculosis (TB) is the leading cause of infectious diseases affecting the 2 billion people worldwide. To improve the current method of treatment a synthetic polymeric anti-TB nanodrug delivery system was attempted. A series of PLGA polymers with different molar feed ratios i.

Adsorption-desorption studies of indigocarmine from industrial effluents by using deoiled mustard and its comparison with charcoal.

Deoiled mustard obtained from local oil mills has been used as an inexpensive and effective adsorbent for the removal of indigocarmine dye from industrial effluents. The influence of various factors on the adsorption capacity has been studied by batch experiments. The adsorption studies validate both Langmuir and Freundlich adsorption isotherms.

Simultaneous RP-HPLC Estimation of Cefpodoxime Proxetil and Clavulanic Acid in Tablets.

A new, simple, precise, rapid and accurate RP-HPLC method has been developed for the simultaneous estimation of cefpodoxime proxetil and clavulanic acid from pharmaceutical dosage forms. The method was carried out on a Zorbax Eclipse XDB 5 mu C 18 (150x4.6 mm) column with a mobile phase consisting of acetonitrile:50 mM potassium dihydrogen phosphate buffer (pH 3.

Genotype phenotype correlation in Wilson's disease within families--a report on four south Indian families.

Aim: To study the genotype phenotype correlation in Wilson's disease (WD) patients within families.

Methods: We report four unrelated families from South India with nine members affected with WD. Phenotype was classified as per international consensus phenotypic classification of WD.

DNA methylation profile at the DNMT3L promoter: a potential biomarker for cervical cancer.

Epigenetic events play a prominent role during cancer development. This is evident from the fact that almost all cancer types show aberrant DNA methylation. These abnormal DNA methylation levels are not restricted to just a few genes but affect the whole genome.

ATP7B mutations in families in a predominantly Southern Indian cohort of Wilson's disease patients.

Objective: To analyze ATP7B mutations in Wilson's disease (WD) patients from the Indian subcontinent and to correlate these with WD phenotype.

Methods: We studied 27 WD patients from 25 unrelated families. Twenty-two families were from three southern Indian states - Tamil Nadu andhra Pradesh and Kerala.

Portal biliopathy.

A young male with portal venous thrombosis presented with obstructive jaundice, due to common bile duct stricture secondary to portal biliopathy.

Unusual presentation of a retroperitoneal lymphangioma.

A 3 year old child presented with hemorrhagic ascites of short duration. Based on clinical manifestation and investigations a differential diagnosis of peritoneal tuberculosis, pancreatic ascites or malignant ascites was considered. Laparotomy revealed a huge retroperitoneal cystic lymphangioma confirmed by histopathology.

Hypereosinophilic syndrome.

Hypereosinophilic syndrome is a leukoproliferative disease characterised by sustained overproduction of eosinophils. The three diagnostic criteria for this disorder are (1) Eosinophilia of greater than 1500 cells/ml, persisting for longer than 6 months, (2) lack of another diagnosis to explain the eosinophilia and (3) signs and symptoms of organ involvement. We report a 15-year-old boy who was diagnosed as Hypereosinophilic syndrome based on these criteria.