Publications by authors named "Mala George Otieno"
Article Synopsis
- Previous research suggests that patients of African ancestry may not respond as well to certain hypertension medications, leading to continued use of these without solid evidence in Ethiopia.
- This study compared the effectiveness of three antihypertensive drugs (nifedipine, enalapril, and hydrochlorothiazide) on blood pressure reduction in Ethiopian patients from November 2016 to April 2017, using a randomized method.
- Results showed that nifedipine significantly reduced systolic blood pressure more than the other drugs, but there was no significant difference in diastolic blood pressure effects among the groups.
Background: Although there are established drugs for treatment of cardiovascular diseases, due to adverse effects these drugs may not be clinically applicable to all patients. Recent trends have seen the emergence of drugs which act on funny current channels to induce selective heart rate reduction. Ivabradine is one such drug developed for coronary artery disease and heart failure.
View Article and Find Full Text PDF