Publications by authors named "Mala D"

Article Synopsis
  • The FDA has approved lecanemab for early-stage Alzheimer's disease, marking a significant advancement in treating neurodegenerative conditions but also presenting various challenges for healthcare institutions.
  • There is a lack of resources for institutions to effectively establish and manage a lecanemab treatment program, prompting the need for a structured framework.
  • The report outlines a three-stage implementation study (feasibility assessment, operations, and monitoring), concluding that lecanemab's clinical integration is feasible with proper project management, financial sustainability analysis, and efficient electronic record tools.
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Background: Recently, progress has been made toward understanding the efficiency of polymer composites with natural fibres. With the hope of enhancing the characteristics of polymer composites supplemented with natural fibres in a watery environment, TiO2 nanoparticles have been used to improve their performance in the field.

Method: These nanoparticles were filled in luffa-epoxy components at 1, 3, and 5 % volume fractions.

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Rheum australe is an endangered medicinal herb of high altitude alpine region of Himalayas and is known to possess anti-cancerous properties. Unlike many herbs of the region, R. australe has broad leaves.

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Inflammation and oxidative stress are closely linked patho-physiological processes which occur concurrently in many diseased conditions. Recently, interdependence between these two processes explains the antioxidant paradox associated with failure to select appropriate agents required for prevention of diseases known to be induced by oxidative stress. Present study established the overlapping anti-inflammatory and anti-oxidative potential along with bio-accessibility of milk casein derived tripeptide (LLY).

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It is unclear why many with diabetes develop foot ulcers (DFU) and why some do not heal. It could be associated with genetic variation. We have previously shown that NOS1AP variation is associated with lower extremity amputation in those with diabetes and that circulating stem progenitor cell concentration (SPC) is associated with impaired foot ulcer healing in those with diabetes.

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A 2-Cys peroxiredoxin cDNA (CjPrx) was isolated and characterized from Caragana jubata, a temperate/alpine plant species of high altitude cold desert of Himalaya and Eurasia. The cDNA obtained was 1,064 bp long consisting of an open reading frame of 789 bp encoding 262 amino acids. The calculated molecular mass of the mature protein was 28.

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The present work was conducted to understand the basis of adaptation in Caragana jubata in its niche environment at high altitude cold desert of Himalaya. Molecular data showed predominance of genes encoding chaperones and those involved in growth and development at low temperature (LT), a major cue operative at high altitude. Importantly, these genes expressed in C.

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Background: Negative interference of bilirubin with assessment of creatinine concentration is generally known from the biochemical aspect. The objective of the presented work was to find the bilirubin level and creatinine concentration where this phenomenon has actually a clinical impact.

Methods And Results: In 200 samples selected at random the bilirubin and creatinine levels were examined by the classical Jaffé method and a method where the effect of bilirubin is suppressed.

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The purpose of this study was to examine the accuracy of translation and to test the validity of the Greek version of the General Health Questionnaire (GHQ). In the translation study, the English and the Greek versions of the GHQ were administered to a sample of 50 bilingual respondents. The internal consistency, item-by-item and the subject-by-subject analysis have shown that the 2 versions are equivalent and therefore the Greek translation is highly accurate.

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