Chromogenic hybridization reveals specific expression pattern of long non-coding RNA in formalin-fixed paraffin-embedded specimen.

Long non-coding RNA (lncRNA) plays an important role in the regulation of gene expression in normal and cancer cells. We previously discovered a novel tumor-suppressive lncRNA, , in prostate cancer cells. Subsequent studies have demonstrated that is dysregulated in various malignancies and exhibits a tumor-suppressive or pro-oncogenic function.