A retrospective study comparing interventions by oncology and non-oncology pharmacists in outpatient chemotherapy.

Background: The differences in the clinical pharmacy services (CPS) provided by oncology and non-oncology pharmacists have not been sufficiently explained.

Aim: This study aimed to demonstrate the differences in direct CPS provided by oncology and non-oncology pharmacists for patients and physicians, and to assess the potential impact of these services on medical costs.

Methods: We retrospectively examined CPS provided by oncology and non-oncology pharmacists for outpatients who underwent chemotherapy between January and December 2016.

Beneficial effects of curcumin on antitumor activity and adverse reactions of doxorubicin.

Many medicines used in cancer chemotherapy decrease the quality of life (QOL). It is believed that an increase in food intake during cancer chemotherapy may produce an improvement in QOL. Curcumin is widely used as a coloring and flavoring agent in food.

Efficacy of theanine is connected with theanine metabolism by any enzyme, not only drug metabolizing enzymes.

Theanine increases the antitumor effect of doxorubicin (DOX) with decreasing adverse reaction. We clarified the mechanism by which theanine decreases the adverse reaction of DOX on any metabolizing enzymes of theanine. There was no change in the activity of any CYPs and the cytochrome P450 content by theanine treatment.