Publications by authors named "Maki Nakajima"

BACKGROUND: Constipation in patients with Parkinson disease (PD) adversely affects motor symptoms, making defecation management critical. Sleep disturbance is another common complaint in patients with PD (PWP). Associations between sleep disturbances and constipation have been reported in recent studies on PD.

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Article Synopsis
  • This study explores lifestyle factors linked to metabolic syndrome (MetS) among urban Cambodians, using health checkup data from a private hospital in Phnom Penh involving 5,459 participants.
  • The overall prevalence of MetS was 56.6%, with higher rates in men (60.4%) compared to women (52.6%).
  • Key lifestyle factors correlated with MetS included eating quickly, walking speed, and alcohol consumption, with distinct associations for men and women regarding meal habits and sleep.
  • Emphasizing health education and lifestyle interventions could help mitigate MetS risk in Cambodia.
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The objectives of this study were to examine the association between urinary excretion of cadmium (U-Cd), copper (U-Cu), and zinc (U-Zn) and the severity of two different indicators of renal toxicity (urinary excretion of beta2-microglobulin [U-beta2-MG] and metallothionein [U-MT]) in Cd-exposed subjects compared to controls, and to assess the physiologic mechanisms by which the exposure to environmental Cd affects U-Cd, U-Cu, and U-Zn. The target population included 3508 Cd-exposed and 294 nonexposed participants who received a health survey conducted among the population of the Kakehashi River basin. Increases of U-Cd, U-beta2-MG, and U-MT in the Cd-exposed population were observed relative to excretion of these substances in controls.

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