Characteristics of azole-resistant Aspergillus fumigatus attached to agricultural products imported to Japan.

Due to the increase in the number of azole-resistant Aspergillus fumigatus, there is an urgent need of data to predict future trends and prevent further spreading. The intercountry transfer of resistant A. fumigatus on plant bulbs have been reported.

Detection of invasive pulmonary aspergillosis in mice using lung perfusion single-photon emission computed tomography with [99mTc]MAA.

There is an urgent need for development of better diagnostic strategies to improve outcomes in patients with invasive pulmonary aspergillosis (IPA). We hypothesized that lung perfusion single-photon emission computed tomography (SPECT) may be more sensitive and specific than computed tomography (CT) of the chest for detection of IPA because it is an angioinvasive pulmonary infection with characteristics that are different from those of bacterial pneumonia. We used SPECT with injection of technetium-99m-labeled macroaggregated albumin ([99mTc]MAA) to measure pulmonary perfusion in noninfected mice, mice with IPA, and mice with bacterial pneumonia.

[A case report of Kimura's disease causing visual dysfunction with remarkable eyelid swelling].

Purpose: We report a case of Kimura's disease involving the eyelids, presenting with bilateral eyelid swelling so severe that the eyelids could not be opened.

Case: A 37-year-old man presented with eyelid swelling and was unable to open both eyelids. He noted swelling and mass of bilateral eyelids since a year previously, and the masses enlarged gradually impairing eye-opening.

Correlation between high-resolution optical coherence tomography (OCT) images and histopathology in an N-methyl-N-nitrosourea-induced retinal degeneration rat model.

Background: Recent research on macular diseases has prompted investigations into the condition of the intersection between the inner and outer segments (IS/OS), and its relationship with retinal photoreceptor abnormalities. Because the correlation between optical coherence tomography (OCT) images and histopathology is unclear, the authors compared them in an N-methyl-N-nitrosourea (MNU)-induced photoreceptor degeneration rat model.

Methods: MNU (60 mg/kg), which is toxic to photoreceptors, was injected in 12 Brown Norway rats.