Silviridoside: A New Triterpene Glycoside from with Promising Antioxidant and Enzyme Inhibitory Potential.

A new triterpene glycoside, silviridoside, was isolated from the aerial parts of (Caryophyllaceae) using different chromatographic techniques. The structure of silviridoside was comprehensively elucidated as 3-β-D-galacturonopyranosyl-quillaic acid 28--β-D-glucopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→3)]-β-D-fucopyranosyl ester by one- and two-dimensional nuclear magnetic resonance (NMR) spectroscopy and high-resolution mass spectrometry (HR-MS). Silviridoside showed promising antioxidant activity in different antioxidant assays such as 2,2-diphenyl-1-picrylhydrazyl (DPPH) (2.

Withanolides from L.

The compounds (17,20,22,24,25)-5β,6β:20,24-diep-oxy-4β,25-dihy-droxy-1-oxowith-2-en-26,22-olide and (20,22)-5α,14α,20-Trihy-droxy-1-oxo-6α,7α-ep-oxy-witha-2-enolide were isolated from a chloro-form extract of the aerial parts of L. (Solanaceae). Two products were isolated from the chromatographic separation extract.

Integration of drug safety monitoring in tuberculosis treatment programmes: country experiences.

New drugs and shorter treatments for drug-resistant tuberculosis (DR-TB) have become available in recent years and active pharmacovigilance (PV) is recommended by the World Health Organization (WHO) at least during the early phases of implementation, with active drug safety monitoring and management (aDSM) proposed for this. We conducted a literature review of papers reporting on aDSM. Up to 18 April, 2019, results have only been published from one national aDSM programme.

Risk factors for unfavourable treatment outcomes among rifampicin-resistant tuberculosis patients in Tajikistan.

Setting: Tajikistan is among the 30 countries with the highest multidrug-resistant tuberculosis (MDR-TB) burden.

Objective: To investigate the risk factors for unfavourable treatment outcomes among rifampicin-resistant (RR)/MDR-TB patients.

Design: Retrospective medical chart review of RR/MDR-TB patients enrolled for treatment in 2012-2013.

Risk factors associated with loss to follow-up from tuberculosis treatment in Tajikistan: a case-control study.

Background: There are very few studies on reasons for loss to follow-up from TB treatment in Central Asia. This study assessed risk factors for LTFU and compared their occurrence with successfully treated (ST) patients in Tajikistan.

Methods: This study took place in all TB facilities in the 19 districts with at least 5 TB patients registered as loss to follow-up (LTFU) from treatment.

TB case detection in Tajikistan - analysis of existing obstacles.

Background: Tajikistan National TB Control Program.

Objective: (1) To identify the main obstacles to increasing TB Detection in Tajikistan. (2) To identify interventions that improve TB detection.

[Quantitative evaluation of latent gastrointestinal hemorrhage in patients with iron deficiency anemia (preliminary report)].

Radiologic investigation of concealed gastro-intestinal hemorrhage with 51Cr was conducted for its detection and quantitative estimation in 102 patients with iron-deficiency anemia (IDA), loss of blood from the digestive tract was detected in 52 of them. A definite relationship was noted between the volume of hemorrhage and the disease responsible for the development of IDA. Moderate hemorrhage from 2.