Delta infection in children with chronic viral hepatitis B.

The incidence and clinical features of chronic viral hepatitis B associated with the delta infection were studied in 300 children between one and 14 years in age. Anti-delta was found in 42 (14%) of 300 children with chronic viral hepatitis B, predominantly in patients with chronic active hepatitis who had anti-HBe; exacerbations were found in 11 of 12 children with anti-delta, but in only four of 12 children without these antibodies. These findings confirm the assumption that the process of exacerbation in patients with chronic active hepatitis and anti-HBe may be related to super-infection induced by the delta virus.

[Effectiveness of cytochrome P-450 inducer Benzonal in the treatment of acute hepatitis].

Forty-six patients with acute viral hepatitis (AVH) varying in severity received standard therapy. Twenty of them were given an adjuvant 6-day course of benzonal. The activity of liver monooxygenase was evaluated before, after treatment (for 6-8 days) and at the height of the disease using antipyrine++ test.

[Hypolipidemic, hypocholesterolemic and antisclerotic action of the rotenoid glycoside amorphin].

Amorphin--24-vicyanoside (C34H4O16(2)H2O)--in a dose of 10 mg/kg orally decreases the content of cholesterol, total lipids, atherogenic lipoproteids in the blood and organs of intact rats and rats with endogenous or ethanol hyperlipemia, inhibits the development of experimental atherosclerosis in rabbits induced by the combination of risk factors (cholesterol + glucose + hypodynamia), decreases the content of lipids in the blood and organs (especially in aorta), prevents the development of morphological manifestations of the aorta atherosclerosis.