[Mono- and combination therapy with the mexidol in young patients with cerebral angiodystonia].

Aim: To evaluate an effect of mono- and combined therapy with mexidol in young patients with cerebral angiodystonia.

Material And Methods: Ninety patients (38 men and 52 women, aged from 25 to 44 years) with autonomic dysfunction syndrome in the form of asthenoautonomic and cephalgic syndromes treated with mexidol (group 1, 30 patients), vinpocetine (group 2, 30 patients) and with the combination of these drugs (group 3, 30 patients) were included in the study. Cerebral hemodynamics was assessed using the algorithm of complex ultrasound study, autonomic regulation with the analysis of heart rate variability, functional microcirculation with laser Doppler flowmetry before and 10 days after treatment.

[The use of L-lysine aescinat in the treatment of microcirculatory disturbances in patients young and middle age with violation of the intracranial venous outflow].

Aim: To study the efficacy of L-lysine aescinat in the treatment of vascular and microvascular disorders in patients with cerebral venous dystonia.

Material And Methods: Sixty-eight patients, 25 male and 43 female, aged from 25 to 56 years, with disturbances of venous cerebral blood circulation and venous outflow difficulties were examined. The examination included the assessment of cerebral hemodynamics using the algorithm of complex ultrasound examinations and functional status of the microcirculation by the laser Doppler flowmetry (LDF) at baseline and 10 days after treatment with L-lysine aescinat.