Using demographic, psychosocial, behavioural and safety-related factors to assess cyclists' behaviour: A comparative approach across 19 countries.

This Data in Brief (DiB) article presents the differences in cycling behaviors related to violations, errors, and positive behaviors by region. The study data were collected by means of a structured questionnaire applied to a full sample of 7,001 participants from 19 countries, distributed over 5 continents. This paper proposes descriptive statistics, as well as common statistical tests.

Features of the crystal structure and surface of superprotonic conductor caesium hydrogen sulfate phosphate.

The crystal structure of superprotonic conductor caesium hydrogen sulfate phosphate [Cs(HSO)(HPO)] have been analyzed using neutron diffraction methods. Additionally, its structure and surface layers have been investigated using atomic force microscopy. From the diffraction data obtained, Fourier syntheses of neutron scattering densities were calculated, and the localization of hydrogen atoms and the parameters of three types of hydrogen bonds in the crystal structure were accurately determined.

Identification of Key Genes Involved in Response to or spp. Infections in Human Cell Lines and in Mouse Organs.

Bacterial infections represent an unsolved problem today since bacteria can evade antibiotics and suppress the host's immune response. A family of TRIM proteins is known to play a role in antiviral defense. However, the data on the involvement of the corresponding genes in the antibacterial response are limited.

[The relationship of vascular complications with cerebrovascular reactivity and endothelial dysfunction in patients with obstructive sleep apnea].

Objective: To assess the relationship of vascular complications with cerebrovascular reactivity (CVR) and endothelial dysfunction in patients with obstructive sleep apnea (OSA).

Material And Methods: One hundred and twelve patients were examined. The patients were stratified into the main group with moderate and severe OSA and the control group without apnea.

The problem of the risk of development of infection of surgical obstetric wound after cesarian section in women of the Kirov region.

Over the past decade, the frequency of abdominal delivery in Russia has increased to an average of 25 %. The widespread use of abdominal delivery has not been without an increase in the incidence of complications. Among them is an infectious complication of a surgical obstetric wound (ICD O86.

Monitoring and assessment of Cs and Sr radioactive isotopes in the 'soil - rhizosphere - sedge' system of the Yenisei River floodplain (near impact zone of Krasnoyarsk MCC, Russia).

Radiocaesium and radiostrontium contamination in the 'soil - rhizosphere - plants (aerial parts)' system was monitored in the floodplain ecosystem of the Yenisei River in the near impact zone of the Krasnoyarsk Mining and Chemical Combine (MCC). The monitored system included soil, rhizosphere, and sedge vegetation on islands and the river's east bank. The Cs and Sr specific activities displayed intricate space and time patterns controlled by the river water level, including the time and duration of floods and their correlation with the sedge vegetation season.

Human TAF-Iα promotes oncogenic transformation via enhancement of cell proliferation and suppression of apoptosis.

Template activating factor-I (TAF-I) is a multifunctional protein involved in various biological processes including the inhibition of histone acetylation, DNA replication, cell cycle regulation, and oncogenesis. Two main TAF-I isoforms with different N-termini, TAF-Iα and TAF-Iβ (SET), are expressed in cells. There are numerous data about functional properties of TAF-Iβ, whereas the effects of TAF-Iα remain largely unexplored.

Fragmented QRS as a marker of coronary atherosclerosis severity evaluated by the Gensini score.

Background: QRS fragmentation (fQRS) represents a marker of local myocardial fibrosis, especially in patients with CAD (coronary artery disease). However, little is known about the association between fQRS and the severity of coronary atherosclerosis as defined by the Gensini score.

Objective: To identify the angiographic and echocardiographic characteristics of patients with suspected CAD depending on the location and extent of fQRS.

Human TRIM14 protects transgenic mice from influenza A viral infection without activation of other innate immunity pathways.

TRIM14 is an important component of innate immunity that defends organism from various viruses. It was shown that TRIM14 restricted influenza A virus (IAV) infection in cell cultures in an interferon-independent manner. However, it remained unclear whether TRIM14 affects IAV reproduction and immune system responses upon IAV infection in vivo.

Crystal structure, hydrogen bonds and thermal transformations of superprotonic conductor Cs(SO)(HPO).

Crystals of Cs(SO)(HPO) belong to the family of alkali metal acid salts that show a high protonic conductivity at relatively low temperatures. Such properties make superprotonic crystals an excellent choice for the study of the influence of the hydrogen subsystem on the physicochemical properties and promising materials for energy-efficient technologies. Single crystals of Cs(SO)(HPO) were studied by neutron diffraction methods, optical polarization microscopy, scanning electron microscopy and energy-dispersive X-ray spectroscopy.

[Cognitive impairment in patients with arterial hypertension depending on the presence of risk factors for chronic kidney disease at the sanatorium stage].

Unlabelled: Vascular cognitive disturbances are widespread in patients with arterial hypertension, especially when attached to arterial hypertension of chronic kidney disease. Each of these diseases has a negative impact on brain vessels and may contribute to cognitive deficits.

The Purpose Of The Study: To evaluate the neuropsychological profile and determine the risk of cognitive impairment in patients with arterial hypertension depending on the presence or absence of risk factors for chronic renal disease at the sanatorium stage.

Estimation of the Mutagenic Potential of 8-Oxog in Nuclear Extracts of Mouse Cells Using the "Framed Mirror" Method.

We propose an improved earlier described "mirror" method for detecting in cell nuclear extracts mutations that arise in DNA during its replication due to the misincorporation of deoxyadenosine-5'-monophosphate (dAMP) opposite 7,8-dihydro-8-oxoguanine (8-oxoG). This method is based on the synthesis of a complementary chain ("mirror") by nuclear extracts of different mice organs on a template containing 8-oxoG and dideoxycytidine residue (ddC) at the 3'‑end. The "mirror" was amplified by PCR using primers part of which was non-complementary to the template.

Parkinson's Disease-Associated Changes in the Expression of Neurotrophic Factors and their Receptors upon Neuronal Differentiation of Human Induced Pluripotent Stem Cells.

Parkinson's disease (PD) is a neurodegenerative pathology resulting from the degeneration of dopaminergic (DA) neurons in the substantia nigra (SN). Neurotrophic factors (NTFs) and their receptors are key regulators of the survival, differentiation, and development of neurons. However, the role of these factors in the pathogenesis of PD is still unclear.

[Radical cystectomy: therapeutic aspects of preoperative and early postoperative management].

Aim: to improve the results of radical cystectomy by optimization of patient preparation for surgery and early postoperative care.

Materials And Methods: A total of 136 patients who underwent radical cystectomy and either orthotopic ileal neobladder or ileal conduit formation were included in the study. Brikkers operation was performed in 92 patients (76% men and 24% women) aged from 39 to 83 years, while in 44 patients (97.

[Depressive disorders and diabetes mellitus in children and adolescents].

Aim: To clarify the role of depressive disorders and personality traits in the pathogenesis of diabetes mellitus type I in children and adolescents.

Material And Methods: One hundred and three patients with diabetes, aged from one year nine months to 17 years, mean 9.7±0.

[Emotional disorders in patients with controlled hypertension].

Aim: To conduct a comprehensive examination of patients with controlled hypertension, including assessment of the functional state of the cardiovascular system, vegetative and psycho-emotional status.

Material And Methods: The study involved 80 patients (51 men, 29 women) divided into 2 groups: 60 patients with essential hypertension (EH) without concomitant severe pathology and normal blood pressure during the preceding 3 months (group 1) and 20 healthy patients without EH (group 2). Anthropometric parameters (height, weight, body mass index), parameters of central hemodynamic (heart rate, systolic and diastolic blood pressure), vegetative status (vegetative Kerdo index), mental and emotional status (SCL-90R, Leonhard questionnaire, HADS, SF-36, MPQ) were assessed.

[Cognitive therapy of depressive rumination].

Modern approaches to the therapy of depressive ruminations are reviewed. Depressive ruminations are thought to underlie and maintain depression. The authors describe different forms of ruminations and present the analysis of depressive ruminations and the role of childhood experience in their development as well as cognitive-behavioral techniques used for their correction.

Effect of cationic substitution on the double-well hydrogen-bond potential in [K(NH)]H(SO) proton conductors: a single-crystal neutron diffraction study.

The structure of the mixed crystal [K(NH)]H(SO) as obtained from single-crystal neutron diffraction is compared with the previously reported room-temperature neutron structure of crystalline KH(SO). The two structures are very similar, as indicated by the high value of their isostructurality index (94.8%).

The artificial and natural isotopes distribution in sedge (Carex L.) biomass from the Yenisei River flood-plain: Adaptation of the sequential elution technique.

The study of migration pathways of artificial isotopes in the flood-plain biogeocoenoses, impacted by the nuclear fuel cycle plants, requires determination of isotope speciations in the biomass of higher terrestrial plants. The optimal method for their determination is the sequential elution technique (SET). The technique was originally developed to study atmospheric pollution by metals and has been applied to lichens, terrestrial and aquatic bryophytes.

The Transcriptional Changes of trim Genes Associated with Parkinson's Disease on a Model of Human Induced Pluripotent Stem Cells.

Over the last few years, in vitro models, based on patient-derived induced pluripotent stem cells (iPSCs), have received considerable attention for modeling different neurodegenerative disorders. Using this model, we analyzed transcription of 15 tripartite motif (trim) genes in iPSCs, derived from the different groups: Parkinson's disease (PD) patients bearing mutations in different genes, patient with the sporadic form of PD, and the healthy individuals. The transcription was observed during neuronal differentiation of the cells in vitro into neuronal stem cells and terminally differentiated neurons.

[THE PROGRAM OF PHYSICAL REHABILITATION FOR PATIENTS WITH CORONARY HEART DISEASE AND HYPERTENSIVE DISEASE].

The authors demonstrate the importance of individual criteria for the choice of dosed physical load for the patients with cardiological problems during hospitalization. The analysis of the functional state and hemodynamic parameters included 68 patients with various cardiovascular diseases before and after performance of the special program of physical rehabilitation. The results suggest high efficiency of the proposed treatment and good prospects for further studies in this field.

[Effect of Ultrasmall Gold Nanoparticles on the Murine Native Sperm Chromatin].

The effects of ultrasmall (2-3 nm) gold nanoparticles on native epididymal sperm chromatin of CBAxC57BL/6 hybrid mice and 129/IMG mice with a mutation in the DNA-polymerase iota gene were studied. It is shown that for both mouse strains after sperm incubation in a solution containing Au nanoparticles, at 23, 37 and 60 degrees C for 30 min followed by 1 hour treatment in dithiothreitol solution, a decrease in the number of nuclei with fully decondensed chromatin was observed compared with the control. Though, the manifestation of this effect in the population of 129/IMG mice mature sperm, was weaker.