[Therapeutic compliance and its pharmaceutical aspects. Basic research].

In present-day drug therapy, the level of therapeutic compliance is a marked professional problem. Its consequences are a challenge for providers of health care and a concern for pharmacists as subjects working in immediate contact with the general public of patients. The present paper reports an evaluation of the level of compliance and analyses its components.

[Pharmacies during the transformation of health care. IV. Sociologic study of pharmacy service].

In Slovakia, similarly as in the Czech Republic, marked changes in the pharmaceutical services have gradually been taking place since 1990. Principal legal and organizational changes have been connected also with the extent and standard of provided pharmaceutical services. The present paper reports the results of a questionnaire research regarding the evaluation of the standard of pharmaceutical services in the year 1995 where there existed both state-owned and private public pharmacies.

The pharmacoepidemiological phenomenon of age-dependent drug consumption and analysis of its regression models.

A randomized pharmacoepidemiological full-year, 7x realized experiment was carried out with the purpose of analyzing the age dependence of drug volumes consumed by the population, using financial and physical measuring units to express per-capita consumption. The experiment was performed for a complete metropolitan population, representing 0.5 million people.

Pharmaco-epidemiological study of drug consumption in the preproductive age period.

Based on the global hypothesis of drug consumption being a function of human age and growing with its increase, an analysis of that dependence was carried out in the preproductive interval of the human lifetime. The experiment included a total metropolitan population of 450,000, involving all outpatient prescriptions of all physicians in the area. The paper shows results obtained over a period of two years.

[Demographic-statistical analysis of pharmacotherapy with emphasis on the geriatric population].

The present paper is a contribution to the field of population pharmacoepidemiology and presents an analysis of the effect of the determinant of age on the magnitude of requirements for medicines, particularly with regard to gerontological population. The paper reports both demographic and pharmacoepidemiologic analysis of pharmacotherapy and formulates a trend of development in connection with expected demographic ageing of the Slovak population. The results reported in the paper document the demographic-health background of pharmacotherapy and point to some population connections of it.

[Polyvalent antibiotics in ambulatory practice].

The present paper analyzes the consumption of antibiotics from the viewpoint of the diagnosis, specialization of the prescribing physician, and the age and sex of the out-patients. The analysis concerns the prescription within two months in a pharmacy at a policlinic. The results are presented according to the frequency of diagnosis, polyvalence of the antibiotics and the specialization of the prescribing physician.

[Substitutional relations in the expression of drug consumption].

The present paper analyzes the formal equivalence of expressing the consumption of medicines in financial and physical units. The study was carried out on a representative sample of population; for the sake of the need of analytical expression also the factor of the age in the consumption of drugs measured per 1 inhabitant was taken into consideration. A highly close relationship between the two specific variables is observed.

[Sex as a factor in drug consumption].

Based upon the hypothesis on the diverse dependency of drug consumption on the sex of population as its influencing factor, this relationship was closely studied. The dynamics of the dependency of large urban population has been analysed for a period of 4 years. Important differences in the dependency on sex and age have been found.

[Long-term evaluation of the relation of demographic and health indicators to drug utilization].

Indicators of demographic and medical statistics display different relationships at the level of drug consumption and from these relationships different potential influences may be derived. The relationship is expressed exactly and because it develops with time its developmental trends are analyzed on a nation-wide scale in the course of 17 years. The period of analysis permits to formulate some conclusions on the stability of this relationship with regard to individual essential factors.

[Parallels in drug utilization--II].

The author analyzes indicators of drug consumption at the regional level in the CSSR and the main towns. The analysis covers the period from 1971-1985 and pertains to the following indicators: A. Expenditure on drugs per day of treatment by functional types of health institutions.

[The effect of age factors on drug utilization in an urban population].

The present paper analyzes the consumption of drugs in the out-patient health care for city population in relation to age and sex. An automated information system of processing of medical prescriptions by means of computer technique was used. Drug consumption is expressed in the form of costs.

[Polyvalency of drugs and its importance in utilization analysis].

In general, morbidity is considered the primary factor in the consumption of drugs. The relationship between the treated nosological unit and the consumption of a given drug for its therapy is, however, not unequivocal and this complicates the quantification of the influence of morbidity on the consumption of drugs. This property of drugs is called in the submitted paper polyvalency or ambivalency.

[Parallels in drug consumption. I].

Drug consumption, expressed in indicators of departmental statistics is the basis of chronological series the development and trend of which is assessed. On this basis parallelisms of these indicators were followed up in 1971-1985. The method applied was used to formulate differences in drug consumption with regard to regional variations, and differences with regard to the functional type of health facilities.