Human schistosomiasis is a chronic and debilitating neglected tropical disease caused by parasitic worms of the genus Schistosoma. It is endemic in many countries in sub-Saharan Africa. Although there is currently no vaccine available, vaccines are in development.
View Article and Find Full Text PDFTo fully comprehend each pesticide's behavior and interactions with soil and the environment, a thorough and nuanced analysis of each one is thought necessary. In this study, 10 randomly selected heterogeneous soil samples, each with distinct characteristics, were subjected to sorption trials as well as disintegration tests using biodegradation, hydrolysis, and photolysis. For sorption tests, the batch equilibrium approach was used, which revealed a dependence on the soils' physicochemical characteristics.
View Article and Find Full Text PDFPhospholipid scramblase 1 (PLSCR1) is an antiviral interferon-stimulated gene (ISG) that has several known anti-influenza functions such as interfering with viral nuclear import, regulating toll-like receptor (TLR) 9 and potentiating the expression of other ISGs. However, the exact mechanisms of anti-flu activity of PLSCR1 in relation to its expression compartment and enzymatic activity, and the molecular and cellular mechanisms involved have not been completely explored. Moreover, only limited animal models have been studied to delineate its role at the tissue level in influenza infections.
View Article and Find Full Text PDFActive films based on polyvinyl alcohol (PVA) and chitosan (CS) were developed by encapsulating chamomile essential oil using an emulsification process, followed by adsorption onto activated carbon (AC) to stabilize the oil droplets. Microscopic analysis showed that the average size of the micelles was between 0.1 μm and 1.
View Article and Find Full Text PDFFrequent droughts significantly affect agricultural productivity and highlight the need for effective solutions to improve water availability for crops. This study investigates the potential of chitosan-based hydrogels, biodegradable biopolymers known for their water-retaining properties, to improve soil moisture and promote plant growth during drought periods. Chitosan hydrogels were synthesized using Pluronic F127 and compared with chitosan and chitosan in combination with sodium alginate (CS/Alg-Na).
View Article and Find Full Text PDFBackground: Healthcare provided without attending to patients' religious/spiritual needs contributes to inequities.
Objective: Assess Muslim American views on the importance and accessibility of religious/spiritual resources in hospitals.
Design/participants/main Measures: A survey was distributed at community events and online to self-reported Muslim adults.
Background And Objectives: Cubital tunnel syndrome is the second most common nerve entrapment, and understanding the anatomy is crucial for the success of the nerve release. During ulnar nerve release for cubital tunnel syndrome, a motor branch is frequently encountered crossing anteriorly over the ulnar nerve from its medial/ulnar side proximally to the lateral/radial side distally. Little has been noted about this crossing branch in the literature.
View Article and Find Full Text PDFThis article aims to study the time fractional coupled nonlinear Schrödinger equation, which explains the interaction between modes in nonlinear optics and Bose-Einstein condensation. The proposed generalized projective Riccati equation method and modified auxiliary equation method extract a more efficient and broad range of soliton solutions. These include novel solutions like a combined dark-lump wave soliton, multiple dark-lump wave soliton, two dark-kink solitons, flat kink-lump wave, multiple U-shaped with lump wave, combined bright-dark with high amplitude lump wave, bright-dark with lump wave and kink dark-periodic solitons are derived.
View Article and Find Full Text PDFIn developing countries, orphan legumes stand at the forefront in the struggle against climate change. Their high nutrient value is crucial in malnutrition and chronic diseases prevention. However, as the 'orphan' definition suggests, their seed systems are still underestimated and seed production is scanty.
View Article and Find Full Text PDFHumans suffer from various diseases that require more specific drugs to target them. Among the different potent agents, s serve as good antibacterial agents; however, s are resistant to such antibiotics. The present study was designed to prepare efficient inhibitor amides (12-15) from inexpensive, easily accessible, and bioactive precursors; Morita Baylis Hillman (MBH) adducts (5-8).
View Article and Find Full Text PDFValidamycin A (VA) is one of the antibiotics that have been utilized in agriculture in Asia; nevertheless, there haven't been many investigations on what happens to VA in soil. The rate at which pesticides are adsorbed into the soil must be determined, since their usage in agriculture is growing. In order to accomplish this, the current study investigated the sorption and degradation of VA in ten distinct soil samples via batch equilibrium studies while maintaining strict laboratory controls.
View Article and Find Full Text PDFThe current study explores the (2+1)-dimensional Chaffee-Infante equation, which holds significant importance in theoretical physics renowned reaction-diffusion equation with widespread applications across multiple disciplines, for example, ion-acoustic waves in optical fibres, fluid dynamics, electromagnetic wave fields, high-energy physics, coastal engineering, fluid mechanics, plasma physics, and various other fields. Furthermore, the Chaffee-Infante equation serves as a model that elucidates the physical processes of mass transport and particle diffusion. We employ an innovative new extended direct algebraic method to enhance the accuracy of the derived exact travelling wave solutions.
View Article and Find Full Text PDFIn this report, we present a dual crosslinking hydrogel fiber made from polyamine saccharides chitosan (CS), synthesized through UV polymerization. This process utilizes Irgacure 2959 and N,N'-Methylenebisacrylamide (MBAA) as initiators, followed by immersion in an aluminum chloride (AlCl) solution. The resulting hydrogel incorporates a dual crosslinking mechanism, quantitatively studied via Nuclear Magnetic Resonance (NMR) spectroscopy.
View Article and Find Full Text PDFFront Cell Infect Microbiol
May 2024
Introduction: While astrocytes participate in the CNS innate immunity against herpes simplex virus type 1 (HSV-1) infection, they are the major target for the virus. Therefore, it is of importance to understand the interplay between the astrocyte-mediated immunity and HSV-1 infection.
Methods: Both primary human astrocytes and the astrocyte line (U373) were used in this study.
Reduced insulin sensitivity (insulin resistance) is a hallmark of normal physiology in late pregnancy and also underlies gestational diabetes mellitus (GDM). We conducted transcriptomic profiling of 434 human placentas and identified a positive association between insulin-like growth factor binding protein 1 gene (IGFBP1) expression in the placenta and insulin sensitivity at ~26 weeks gestation. Circulating IGFBP1 protein levels rose over the course of pregnancy and declined postpartum, which, together with high gene expression levels in our placenta samples, suggests a placental or decidual source.
View Article and Find Full Text PDFDegradation of dyes under natural light sources is one of the most active research areas in basic science for greener technology. In this context, the photocatalytic activity of semiconductors has received massive attention in solving water treatment-related issues as these possess enormous potential for degrading organic impurities. Here, we report that barium aluminate (BaAlO, BAO), which has been extensively studied for photoluminescence applications, is found to be a highly potent candidate for photocatalytic activities.
View Article and Find Full Text PDFAccelerating safety assessments for novel agrochemicals is imperative, advocating for setups to present pesticide biodegradation by soil microbiota before field studies. This approach enables metabolic profile generation in a controlled laboratory environment eliminating extrinsic factors. In the current study, ten different soil samples were utilized to check their capability to degrade Ametoctradin by their microbiota.
View Article and Find Full Text PDFJ Allergy Clin Immunol Pract
March 2024
Common symptoms of Chronic Non-atrophic Gastritis (CNAG) include nausea, stomach distension, and abdominal pain. The Houtou Jianweiling Tablet (HTJWT) is a chinese patent medicine (CN1368229A) and it has been used clinically for more than 20 years with proven clinical efficacy in treating CNAG, prompted us to establish the clinical efficacy and safety of HTJWT on patients with mild to moderate CNAG symptoms in Pakistani population. This phase II, double-blind, randomized, parallel-controlled trial was conducted in a single center between November 2022 and February 2023 in Pakistan.
View Article and Find Full Text PDFUnlabelled: Problem description\The University of Nebraska College of Pharmacy is interested in conducting and learning from an inventory of Justice, Equity, Diversity, and Inclusion (JEDI) within the college.
Quality Improvement Methods: An extensive literature review was undertaken to define the terms included in JEDI and to craft a listing of ideal inventory components.
Results Of Cqi Inquiry: The terms used in JEDI were defined and a list of 148 ideal inventory components was created.
J Perianesth Nurs
October 2024
Purpose: Perioperative vision loss (POVL) is a rare and devastating complication following prone spine surgery. Due to the rare nature of this complication, there is limited research available about patient and surgical risk factors that increase the risk of POVL. The objective of this study was to investigate associated risk factors for POVL with use of the National Surgical Quality Improvement Program (NSQIP) database.
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