Peptide-based nanomaterials and their diverse applications.

The supramolecular self-assembly of peptides offers a promising avenue for both materials science and biological applications. Peptides have garnered significant attention in molecular self-assembly, forming diverse nanostructures with α-helix, β-sheet, and random coil conformations. These self-assembly processes are primarily driven by the amphiphilic nature of peptides and stabilized by non-covalent interactions, leading to complex nanoarchitectures responsive to environmental stimuli.

Integration of metal-organic frameworks and clay toward functional composite materials.

Metal-organic frameworks (MOFs) have become increasingly important as a class of porous crystalline materials because of their diverse applications. At the same time, significant progress has been achieved in the field of MOF-based composite materials toward novel applications based on the synergistic effect of two or more different components. Clay materials have been explored recently in MOF chemistry for the synthesis of MOF-clay composites, which are a new class of functional materials synthesized by a cooperative combination of MOFs with clay.

Modulating photophysical properties in a flexible porous host by regulating guest-assisted charge transfer interactions.

The 1D array of electron donor-acceptor chromophoric organic molecules is of paramount importance for photovoltaic, catalytic and optoelectronic applications. Herein, we report coordination driven 1D arrays of an electron-donor guest (fluorene, carbazole, dibenzofuran, and dibenzothiophene) and -phen chelator as an acceptor in a Zn-based porous coordination polymer, {[Zn(-phen)(ndc)]·DMF} (PCP-1). All the guest-encapsulated PCPs were characterized by performing single-crystal structure determinations and showed emission driven by charge transfer.

Unravelling denaturation, temperature and cosolvent-driven chiroptical switching in peptide self-assembly with switchable piezoelectric responses.

Herein, we explore the intricate pathway complexity, focusing on the dynamic interplay between kinetic and thermodynamic states, during the supramolecular self-assembly of peptides. We uncover a multiresponsive chiroptical switching phenomenon influenced by temperature, denaturation and content of cosolvent in peptide self-assembly through pathway complexity (kinetic thermodynamic state). Particularly noteworthy is the observation of chiroptical switching during the denaturation process, marking an unprecedented phenomenon in the literature.

A triazole-based covalent organic framework as a photocatalyst toward visible-light-driven CO reduction to CH.

Solar-light driven reduction of CO to CH is a complex process involving multiple electron and proton transfer processes with various intermediates. Therefore, achieving high CH activity and selectivity remains a significant challenge. Covalent organic frameworks (COFs) represent an emerging class of photoactive semiconductors with molecular level structural tunability, modular band gaps, and high charge carrier generation and transport within the network.

Photocatalytic CO Reduction to Solar Fuels by a Chemically Stable Bimetallic Porphyrin-Based Framework.

Porphyrin-based photocatalysts have emerged as promising candidates for facilitating carbon dioxide (CO) reduction due to their exceptional light-harvesting properties. However, their performance is hindered by complex synthesis procedures, limited structural stability, inadequate CO activation capabilities, and a lack of comprehensive structure-property relationships. This study investigates the performance of a porphyrin-based bimetallic framework, [Cu(TPP)CuMoO] (TPP = tetrapyridylporphyrin), termed for photocatalytic CO reduction.

2D Covalent Organic Framework Covalently Anchored with Carbon Nanotube as High-Performance Cathodes for Lithium and Sodium-Ion Batteries.

Covalent organic frameworks (COFs), featuring structural diversity, permanent porosity, and functional versatility, have emerged as promising electrode materials for rechargeable batteries. To date, amorphous polymer, COF, or their composites are mostly explored in lithium-ion batteries (LIBs), while their research in other alkali metal ion batteries is still in infancy. This can be due to the challenges that arise from large volume changes, slow diffusion kinetics, and inefficient active site utilization by the large Na or K ion.

GFP Chromophore Integrated Conjugated Microporous Polymers toward Bioinspired Photocatalytic CO Reduction to CO.

The development of highly active, durable, and low-cost metal-free catalysts for the photocatalytic CO reduction reaction (CORR) is an efficient and environmentally friendly solution to address significant problems like global warming and high energy demand. In the present study, we have demonstrated the design and synthesis of a donor-acceptor based conjugated microporous polymer (CMP), TPA-GFP, by integrating an electron donor, tris(4-ethynylphenyl)amine (TPA), with a green fluorescent protein chromophore analogue ()-4-(2-hydroxy-3,5-diiodobenzylidene)-1-(4-iodophenyl)-2-methyl-1-imidazol-5(4)-one (o-HBDI-I3) (GFP). In comparison to nondonor 1,3,5-triethynylbenzene (TEB) based TEB-GFP CMP, photocatalytic CO reduction using donor-acceptor based TPA-GFP CMP displays a 3-fold increment of CO production yield with a maximum CO yield of 1666 μmol g at 12 h.

An adsorbate biased dynamic 3D porous framework for inverse CO sieving over CH.

Separating carbon dioxide (CO) from acetylene (CH) is one of the most critical and complex industrial separations due to similarities in physicochemical properties and molecular dimensions. Herein, we report a novel Ni-based three-dimensional framework {[Ni(μ-OH)(μ-OH)(1,4-ndc)](3HO)} (1,4-ndc = 1,4-naphthalenedicarboxylate) with a one-dimensional pore channel (3.05 × 3.

Mild chemistry synthesis of ultrathin BiOS nanosheets exhibiting 2D-ferroelectricity at room temperature.

Modern technology demands miniaturization of electronic components to build small, light, and portable devices. Hence, discovery and synthesis of new non-toxic, low cost, ultra-thin ferroelectric materials having potential applications in various electronic and optoelectronic devices are of paramount importance. However, achieving room-temperature ferroelectricity in two dimensional (2D) ultra-thin systems remains a major challenge as conventional three-dimensional ferroelectric materials lose their ferroelectricity when the thickness is brought down below a critical value owing to the depolarization field.

Microwave Assisted Fast Synthesis of a Donor-Acceptor COF Towards Photooxidative Amidation Catalysis.

The synthesis of covalent organic frameworks (COFs) at bulk scale require robust, straightforward, and cost-effective techniques. However, the traditional solvothermal synthetic methods of COFs suffer low scalability as well as requirement of sensitive reaction environment and multiday reaction time (2-10 days) which greatly restricts their practical application. Here, we report microwave assisted rapid and optimized synthesis of a donor-acceptor (D-A) based highly crystalline COF, TzPm-COF in second (10 sec) to minute (10 min) time scale.

Hydrogen Evolution in Neutral Media by Differential Intermediate Binding at Charge-Modulated Sites of a Bimetallic Alloy Electrocatalyst.

The energy barrier to dissociate neutral water has been lowered by the differential intermediate binding on the charge-modulated metal centers of CoMo sheets supported on Ni-foam (NF), where the overpotential for hydrogen evolution reaction (HER) in 1 M phosphate buffer solution (PBS) is only 50±9 mV at -10 mA cm. It has a turnover frequency (TOF) of 0.18 s, mass activity of 13.

Efficacy and Safety of Oral Metronomic Chemotherapy in Recurrent Refractory Advanced Gynaecological Cancer: An Experience From the Regional Cancer Centre of Eastern India.

Introduction: The outcome of recurrent/metastatic gynaecological malignancy has drastically improved with the introduction of poly(ADP-ribose) polymerase inhibitors and immunotherapy, but the use of these drugs in routine practice is complicated due to access barriers and their high cost in developing countries. The purpose of this study is to present the clinical response, outcome and safety of oral metronomic chemotherapy (OMCT) in resource-limited, financially constrained populations.

Methods: This is a retrospective study on patients with advanced gynaecological cancer treated at Chittaranjan National Cancer Institute, Kolkata, India, from 2021 to 2023.

COF-Topological Quantum Material Nano-heterostructure for CO to Syngas Production under Visible Light.

Efficient solar-driven syngas production (CO+H mixture) from CO and HO with a suitable photocatalyst and fundamental understanding of the reaction mechanism are the desired approach towards the carbon recycling process. Herein, we report the design and development of an unique COF-topological quantum material nano-heterostructure, COF@TI with a newly synthesized donor-acceptor based COF and two dimensional (2D) nanosheets of strong topological insulator (TI), PbBiTe. The intrinsic robust metallic surfaces of the TI act as electron reservoir, minimising the fast electron-hole recombination process, and the presence of 6s lone pairs in Pb and Bi in the TI helps for efficient CO binding, which are responsible for boosting overall catalytic activity.

Modular Gating of Ion Transport by Postsynthetic Charge Transfer Complexation in a Metal-Organic Framework.

Nature's design of biological ion channels that demonstrates efficient gating and selectivity brings to light a very promising model to mimic and design for achieving selective and tunable ion transport. Functionalized nanopores that permit modulation of the pore wall charges are a compelling approach to gain control over the ion transport mechanism through the pores. This makes way for employing a noncovalent supramolecular approach for attaining charge reversal of the MOF pore walls using donor-acceptor pairs that can demonstrate strong charge transfer interactions.

Noncovalent interaction guided selectivity of haloaromatic isomers in a flexible porous coordination polymer.

Porous, supramolecular structures exhibit preferential encapsulation of guest molecules, primarily by means of differences in the order of (noncovalent) interactions. The encapsulation preferences can be for geometry (dimension and shape) and the chemical nature of the guest. While geometry-based sorting is relatively straightforward using advanced porous materials, designing a "chemical nature" specific host is not.

Pore-Confined π-Chromophoric Tetracene as a Visible Light Harvester toward MOF-Based Photocatalytic CO Reduction in Water.

Integrating photoactive π-chromophoric guest molecules inside the MOF nanopore can result in the emergence of light-responsive features, which in turn can be utilized for developing photoactive materials with inherent properties of MOF. Herein, we report the confining of π-chromophoric tetracene () molecules inside the nanospace of postmodified Zr-MOF-808 () with MBA molecules (MBA = 2-(5'-methyl-[2,2'-bipyridine]-5-yl)acetic acid) for effectively utilizing its light-harvesting properties toward photocatalytic CO reduction. The confinement of the molecules as a photosensitizer and the covalent grafting of a catalytically active [Re(MBA)(CO)Cl] complex, postsynthetically, result in a single integrated catalytic system named .

Confining charge-transfer complex in a metal-organic framework for photocatalytic CO reduction in water.

In the quest for renewable fuel production, the selective conversion of CO to CH under visible light in water is a leading-edge challenge considering the involvement of kinetically sluggish multiple elementary steps. Herein, 1-pyrenebutyric acid is post-synthetically grafted in a defect-engineered Zr-based metal organic framework by replacing exchangeable formate. Then, methyl viologen is incorporated in the confined space of post-modified MOF to achieve donor-acceptor complex, which acts as an antenna to harvest visible light, and regulates electron transfer to the catalytic center (Zr-oxo cluster) to enable visible-light-driven CO reduction reaction.

Confining Molecular Photosensitizer and Catalyst in MOF toward Artificial Photosynthesis: Validating Electron Transfer by DRIFT Study.

Exploration of different chemical systems for photocatalytic CO reduction by using sunlight en route to the achievement of artificial photosynthesis stems from global warming and the energy crisis. In this work, we have covalently grafted the molecular photosensitizer (PS) [Ru(MBA)(bpy)]Cl (bpy: 2,2'-bipyridine) and the catalyst [Mn(MBA)(CO)Br] inside the Zr-MOF-808 () nanopore postmodified with 2-(5'-methyl-[2,2'-bipyridine]-5-yl)acetic acid (H-MBA) and developed a single integrated system named for the CO reduction reaction (CORR). is found to be active toward CO-to-CO conversion, with a maximum production of 1027 μmol g after 26 h of reaction having >99% selectivity in the aqueous medium without any additional hole scavenger.

NiCo@NiCoO/NCNT as Trifunctional ORR, OER, and HER Electrocatalysts and its Application in a Zn-Air Battery.

The efficient electrochemical conversion and storage devices can be boosted by the development of cost-effective and durable electrocatalysts. However, simultaneous in-depth understanding of the reaction mechanism is also required. Herein, we report the preparation, characterization, and electrochemical activities of bimetallic NiCo NPs and core-shell NiCo@NiCoO NPs stabilized on N-doped carbon nanotubes (NCNTs).