Purpose: People with sensory impairments (SI) face unique challenges in out-of-home care, especially in oral health (OH) care, compared to the general population. Various assistive technologies (ATs) and media are used to influence OH behaviors and outcomes for individuals with SI. This systematic review (SR) aimed to identify the types of ATs and assess their effectiveness for individuals with SI.
View Article and Find Full Text PDFWhite blood cells (WBCs), also known as leukocytes, are one of the most significant parts of the immune system. They generate antibodies, protect the body from illnesses, and heal wounds. Accurate estimation of WBCs is key for diagnosing cancer, infections, leukemia, lymphoma, and other diseases.
View Article and Find Full Text PDFScrub typhus (ST) is an emerging public health concern in India. Despite being treatable, 20-30% of acute febrile illnesses (AFI) progress to encephalitis in endemic regions. This study aimed to identify early markers for encephalitis development in children hospitalized with AFI and positive Orientia tsutsugamushi (Ots) serology.
View Article and Find Full Text PDFMany refugee camps exist for decades but associated infrastructure needs are only planned for the very short term, including provision of power. This study advocates a shift in approach to sustainable electrification of essential services in refugee camps for lighting, refrigeration, health, water, education, alongside camp operations. Qualitative and quantitative surveys were conducted in refugee camps in Uganda and Bangladesh which assessed the electrical supply needs across such categories.
View Article and Find Full Text PDFThe ion binding to the lipid/water interface can substantially influence the structural, functional, and dynamic properties of the cell membrane. Despite extensive research on ion-lipid interactions, the specific effects of ion binding on the polarity and hydration at the lipid/water interface remain poorly understood. This study explores the influence of three biologically relevant divalent cations─Mg, Ca, and Zn─on the depth-dependent interfacial polarity and hydration of zwitterionic DPPC lipid in its gel phase at room temperature.
View Article and Find Full Text PDFBackground: Protein requirements established for healthy populations may be insufficient to support healthy growth in infants consuming largely cereal-based complementary foods and frequently exposed to enteric pathogens.
Objective: To assess independent and combined effects of protein supplementation and antibiotic treatment on linear growth of infants from 6-12 months of age.
Design: We conducted a 2 x 4 factorial cluster-randomized trial in northwestern Bangladesh, allocating 566 clusters to masked azithromycin (10 mg·kg * 3 d) or placebo at 6 and 9 months of age, and unmasked delivery of an egg white protein-rich blended food supplement (250 kcal; 10 g added protein), a rice-based isocaloric supplement, egg, or nutrition education from 6-12 months.
The objective of this study was the develop of fortified cookies enriched with oats flour and bitter gourd powder and monitoring the effects of these enrichments on the physicochemical, antioxidant, antimicrobial, and sensory attributes. This study was subjected to four treatments: control (0% oats flour and bitter gourd powder), T1 (10% oats flour), T2 (3% bitter gourd powder), and T3 (7% oats flour and 3% bitter gourd powder). Various physical properties of the cookies, including weight, thickness, diameter, spread ratio, baking loss, pH, and color values (L*, a*, and b*), were measured.
View Article and Find Full Text PDFControlled-release microparticles offer a promising avenue for enhancing patient compliance and minimizing dosage frequency. In this study, we aimed to design controlled-release microparticles of Glipizide utilizing Eudragit S100 and Methocel K 100 M polymers as controlling agents. The microparticles were fabricated through a simple solvent evaporation method, employing various drug-to-polymer ratios to formulate different controlled-release batches labeled as F1 to F5.
View Article and Find Full Text PDFAn eco-friendly nitrogen-passivated carbon dot (N-CDs)-based fluorescent sensor was designed for the selective and sensitive detection of thiophanate-methyl, a widely applied fungicide in agriculture. The synthesized N-CDs exhibited robust fluorescence and remarkable photostability, which contributed to the sensor's performance. Notably, the sensor achieved a detection limit as low as 4.
View Article and Find Full Text PDFBackground Artificial intelligence (AI) is revolutionizing healthcare globally by enhancing diagnostic accuracy, predicting patient outcomes, and enabling personalized treatment plans. However, in low- and middle-income countries (LMICs) like Pakistan, the integration of AI into healthcare is limited due to challenges such as lack of funding, provider resistance, and inadequate training. Despite these barriers, there is growing interest among healthcare providers in understanding and adopting AI technologies to improve professional efficiency.
View Article and Find Full Text PDFThe conversion of solar energy into chemical energy or high-value chemicals has attracted considerable research interest in the context of the global energy crisis. Hydrogen peroxide (HO) is a versatile and powerful oxidizing agent widely used in chemical synthesis and medical disinfection. HO also serves as a clean energy source in fuel cells, generating electricity with zero-carbon emissions.
View Article and Find Full Text PDFBackground: Sickle cell disease (SCD) is an autosomal recessive genetic blood disorder. It affects up to 2.6% of the Kingdom of Saudi Arabia population.
View Article and Find Full Text PDFClinical observations indicate a pronounced exacerbation of Cardiovascular Diseases (CVDs) in individuals grappling with Alcohol Use Disorder (AUD), suggesting an intricate interplay between these maladies. Pinpointing shared risk factors for both conditions has proven elusive. To address this, we pioneered a sophisticated bioinformatics framework and network-based strategy to unearth genes exhibiting aberrant expression patterns in both AUD and CVDs.
View Article and Find Full Text PDFIntroduction: Ethnomedicinal plants in Asia offer a promising, low-side-effect alternative to synthetic drugs for treating fungal infections, one of the most widespread communicable diseases caused by pathogenic fungi. Despite being underexplored, the region's rich plant diversity holds the potential for developing effective antifungal drugs. Research is increasingly focused on bioactive compounds from these plants, which show strong antifungal properties and may serve as leads for new drug development.
View Article and Find Full Text PDFObjective: Breast cancer detection is critical for timely and effective treatment, and automatic detection systems can significantly reduce human error and improve diagnosis speed. This study aims to develop an accurate and robust framework for classifying breast cancer into benign and malignant categories using a novel machine learning architecture.
Methods: We propose a dense-ResNet attention integration (DRAI) architecture that combines DenseNet and ResNet models with three attention mechanisms to enhance feature extraction from the BreakHis dataset.
Introduction Cardiorespiratory fitness (CRF) is a key health indicator for assessing optimal physical function and overall well-being. Exploring the early impact of body mass index (BMI) and anthropometric measures on CRF in non-obese individuals is essential for identifying risk factors and guiding preventive strategies to address weight-related health challenges. This study aims to investigate the impact of BMI and anthropometric measures on CRF, focusing on maximal oxygen uptake (VO2max) and metabolic equivalents (METs) in non-obese adult males.
View Article and Find Full Text PDFOur study presents a novel orbit with s-convexity, for illustration of the behavior shift in the fractals. We provide a theorem to demonstrate the escape criterion for transcendental cosine functions of the type Tα,β(u) = cos(um)+αu + β, for [Formula: see text] and m ≥ 2. We also demonstrate the impact of the parameters on the formatted fractals with numerical examples and graphical illustrations using the MATHEMATICA software, algorithm, and colormap.
View Article and Find Full Text PDFAccurately identifying Milankovitch cycles has been a significant challenge in cyclostratigraphic studies, as it is essential for improving geochronology. This manuscript focuses on developing a method that distinguishes Milankovitch cycles from sedimentary noise to enhance stratigraphic precision. Despite their often-conspicuous magnitude, these periodicities frequently intertwine with noise, posing a challenge for conventional spectral analysis.
View Article and Find Full Text PDFThe land use transition plays an important role for terrestrial environmental services, which had a mixed impact of positive and negative on the groundwater and terrestrial water resource. The health of ecological systems and groundwater depends on the mapping and management of land use. The Ganga basin is one of the most densely populated and agriculture-intensive river systems in the South Asia and the world.
View Article and Find Full Text PDFYersinia pestis, a Gram-negative bacterium is the causative agent of the fatal communicable disease plague. The disease had a profound impact on human history. Plague bacteria are usually transmitted to humans through the bite of an infected rat flea.
View Article and Find Full Text PDFElicitation of HIV broadly neutralizing antibodies (bnAbs) by vaccination first requires the activation of diverse precursors, followed by successive boosts that guide these responses to enhanced breadth through the acquisition of somatic mutations. Because HIV bnAbs contain mutations in their B cell receptors (BCRs) that are rarely generated during conventional B cell maturation, HIV vaccine immunogens must robustly engage and expand B cells with BCRs that contain these improbable mutations. Here, we engineered an immunogen that activates diverse precursors of an HIV V3-glycan bnAb and promotes their acquisition of a functionally critical improbable mutation.
View Article and Find Full Text PDFPolymer composites have gained attention due to their multifunctionality and ability to tune properties at multiple scales [...
View Article and Find Full Text PDFNut set is an important determinant of yield and plays a pivotal role in orchard profitability. The complex process of nut setting is governed by numerous factors, with pollination being a critical mechanism. Macadamia cultivars exhibit both self- and cross-pollination.
View Article and Find Full Text PDFHerbal medicine, particularly in developing regions, remains highly popular due to its cost-effectiveness, accessibility, and minimal risk of adverse effects. L., commonly known as turmeric, exemplifies such herbal remedies with its extensive history of culinary and medicinal applications across Asia for thousands of years.
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