Publications by authors named "Maja Ratajczak"
Anesth Analg
September 2007
Article Synopsis
- Ropivacaine, a local anesthetic, is commonly used through epidural methods for managing postoperative pain, but there's limited data on how it behaves in the spinal canal.
- An experiment with sheep involved administering ropivacaine both intravenously and through intrathecal and epidural routes, measuring drug concentrations using microdialysis.
- Results indicated that intrathecal administration led to faster systemic absorption and showed significant differences in how ropivacaine is disposed of in the intrathecal and epidural spaces, revealing low and variable bioavailability of the drug when given epidurally.
