Publications by authors named "Maja Mijac"
Human bocavirus (HBoV) has emerged as a significant pathogen primarily associated with respiratory infections in children. This study aimed to evaluate the clinical relevance of HBoV infection by quantifying viral loads in nasopharyngeal swabs from hospitalized children with acute respiratory infections (ARIs) and investigating correlations with clinical outcomes. A total of 957 children were tested, with HBoV detected in 73 cases (7.
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- Human bocavirus (HBoV) is a respiratory virus that commonly affects children and often appears alongside other respiratory viruses, complicating diagnosis.
- A study compared two testing methods (multiplex PCR and quantitative PCR) for detecting HBoV in cases where it co-occurs with other viruses, analyzing 55 cases.
- Although no significant correlation between the severity of the disease and the amount of HBoV was found, children with higher levels of HBoV and other viruses tended to have longer hospital stays.
Article Synopsis
- Human bocavirus (HBoV) 1 is a significant respiratory pathogen, while the impact of HBoV2-4 is still debated, highlighting the need for ongoing genetic surveillance.
- The study examined 957 respiratory samples from children in Croatia with infections over four years, finding HBoV in 7.6% of cases and a high rate of co-infection at 82.2%.
- Phylogenetic analysis showed that all HBoV sequences belonged to HBoV1, which closely relates to global strains, and the study found no evidence of recombination among the sequences.
Respiratory viral infections are the leading cause of morbidity and mortality in the world; however, there are several groups of viruses that are insufficiently routinely sought for, and can thus be considered neglected from a diagnostic and clinical standpoint. Timely detection of seasonality of certain respiratory viruses (e.g.
View Article and Find Full Text PDFRhinoviruses (RVs) are increasingly implicated not only in mild upper respiratory tract infections, but also in more severe lower respiratory tract infections; however, little is known about species diversity and viral epidemiology of RVs among the infected children. Therefore, we investigated the rhinovirus (RV) infection prevalence over a 2-year period, compared it with prevalence patterns of other common respiratory viruses, and explored clinical and molecular epidemiology of RV infections among 590 children hospitalized with acute respiratory infection in north-western and central parts of Croatia. For respiratory virus detection, nasopharyngeal and pharyngeal flocked swabs were taken from each patient and subsequently analyzed with multiplex RT-PCR.
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- The study focused on the prevalence of Human bocavirus (HBoV) in hospitalized infants and young children with lower respiratory tract infections (LRTI) in Zagreb, Croatia, during the winter of 2016/2017.
- Out of 295 children tested, HBoV was detected in 23.1%, making it the second most common virus after respiratory syncytial virus (RSV), which was found in 59.3% of cases.
- The research indicated that older children were more likely to have HBoV, and 51% of HBoV-positive samples also had another respiratory virus, suggesting that HBoV plays a significant role in respiratory diseases in children.