Triggered contraction of self-assembled micron-scale DNA nanotube rings.

Contractile rings are formed from cytoskeletal filaments during cell division. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes and peptide-functionalized starPEG constructs as synthetic crosslinkers to mimic this process.

Silo discharge of mixtures of soft and rigid grains.

We study the outflow dynamics and clogging phenomena of mixtures of soft, elastic low-friction spherical grains and hard frictional spheres of similar size in a quasi-two-dimensional (2D) silo with narrow orifice at the bottom. Previous work has demonstrated the crucial influence of elasticity and friction on silo discharge. We show that the addition of small amounts, even as low as 5%, of hard grains to an ensemble of soft, low-friction grains already has significant consequences.