Publications by authors named "Maja Gran Erke"
To compare two screening strategies for diabetic retinopathy (DR), and to determine the health-economic impact of including optical coherence tomography (OCT) in a regular DR screening. This cross-sectional study included a cohort of patients (≥ 18 years) with type 1 or 2 diabetes mellitus (T1D or T2D) from a pilot DR screening program at Oslo University Hospital, Norway. A combined screening strategy where OCT was performed in addition to fundus photography for all patients, was conducted on this cohort and compared to our existing sequential screening strategy.
View Article and Find Full Text PDFBackground: Diabetic retinopathy (DR) is the leading cause of adult blindness in the working age population worldwide, which can be prevented by early detection. Regular eye examinations are recommended and crucial for detecting sight-threatening DR. Use of artificial intelligence (AI) to lessen the burden on the healthcare system is needed.
View Article and Find Full Text PDFPurpose: to gain insight into the baseline parameters of a population with diabetes mellitus (DM) included in a pilot diabetic retinopathy (DR) screening program at Oslo University Hospital (OUH), Norway.
Methods: This was a cross-sectional study of a cohort of adult patients (≥18 years) with type 1 or 2 DM (T1D and T2D). We measured the best-corrected visual acuity (BCVA), blood pressure (BP), heart rate (HR), intraocular pressure (IOP), height and weight.
Background/aims: To investigate the association of commonly used systemic medications with prevalent age-related macular degeneration (AMD) in the general population.
Methods: We included 38 694 adults from 14 population-based and hospital-based studies from the European Eye Epidemiology consortium. We examined associations between the use of systemic medications and any prevalent AMD as well as any late AMD using multivariable logistic regression modelling per study and pooled results using random effects meta-analysis.
Article Synopsis
- The study aimed to explore how cardiovascular risk factors like age, BMI, and blood pressure relate to the thickness of various retinal layers, like the ganglion cell-inner plexiform layer (GCIPL).
- The research included data from two rounds of the Tromsø Study, measuring retinal thickness and excluding individuals with diabetes or glaucoma, ultimately analyzing 8,288 participants cross-sectionally and 2,595 longitudinally.
- The findings revealed that GCIPL thickness was notably impacted by age and BMI, with significant relationships identified for blood pressure, emphasizing that weight and blood pressure are important factors for modifying retinal health.
Purpose: Genetic and epidemiologic studies have shown that lipid genes and high-density lipoproteins (HDLs) are implicated in age-related macular degeneration (AMD). We studied circulating lipid levels in relationship to AMD in a large European dataset.
Design: Pooled analysis of cross-sectional data.
Purpose: To investigate whether myopia is becoming more common across Europe and explore whether increasing education levels, an important environmental risk factor for myopia, might explain any temporal trend.
Design: Meta-analysis of population-based, cross-sectional studies from the European Eye Epidemiology (E(3)) Consortium.
Participants: The E(3) Consortium is a collaborative network of epidemiological studies of common eye diseases in adults across Europe.
Article Synopsis
- The study estimates the prevalence of refractive errors like myopia, hyperopia, and astigmatism in adults across Europe using data from various cohort studies between 1990 and 2013.
- Participants included were mainly of European ancestry, with exclusions for those who had undergone eye surgeries that could affect results.
- Key findings highlighted that approximately 30.6% of adults have myopia, particularly high in younger individuals, while overall, more than half of the adult population in Europe experiences some form of refractive error.
Purpose: To project the number of persons with late age-related macular degeneration (AMD) in Scandinavia through 2040.
Methods: Age- and sex-specific prevalence rates of late AMD (choroidal neovascularization and geographic atrophy) from the European Eye Study and the Eye Diseases Prevalence Research Group were applied to the projected Danish, Norwegian and Swedish population from 2012 to 2040.
Results: A total of 187 000 persons aged ≥65 years in Scandinavia are currently affected by late AMD: 47 000 in Denmark, 43 000 in Norway and 97 000 in Sweden.