Objective: To assess whether labour variables (i.e. individuals characteristics, labour characteristics and medical interventions) impact maternal and newborn microbiomes.
The study aimed to replicate previous findings linking five specific SNPs to thrombosis in acute lymphoblastic leukemia patients treated with asparaginase.
Some SNPs, including rs11556218, were found to increase the risk of thrombosis and sensitivity to asparaginase, with variations dependent on treatment protocol and patient characteristics.
The analysis also revealed interactions between factor V Leiden, non-O blood groups, and an increased risk of thrombosis related to asparaginase treatment.