Genetic and environmental perturbations alter the rhythmic expression pattern of a circadian long non-coding RNA, , in mouse liver.

: Long non-coding RNAs (lncRNAs) play a wide variety of biological roles without encoding a protein. Although the functions of many lncRNAs have been uncovered in recent years, the regulatory mechanism of lncRNA expression is still poorly understood despite that the expression patterns of lncRNAs are much more specific compared to mRNAs. Here, we investigated the rhythmic expression of , a novel lncRNA that regulates circadian rhythms.