Publications by authors named "Mais Mazin Al-Hamdani"
Article Synopsis
- Breast cancer has become the most common cancer worldwide, with metastatic cancer being the leading cause of death related to this disease, prompting the development of early detection methods using non-invasive biomarkers.
- Exosomes, which are tiny vesicles released by cancer cells, play a crucial role in transmitting signals and contain noncoding RNAs (ncRNAs) like miRNAs, lncRNAs, and circRNAs that influence various aspects of breast cancer progression, including growth, metastasis, and immune responses.
- The study examines the regulatory mechanisms of exosomes in breast cancer and aims to enhance understanding of the functions of exosomal ncRNAs to identify potential biomarkers and improve treatment strategies.
Article Synopsis
- Metastatic disease and cancer recurrence are major causes of cancer-related deaths, largely driven by circulating tumor cells (CTCs) and disseminated tumor cells (DTCs).
- Liquid biopsy, which uses rare CTCs for early-stage tumor detection, is a promising minimally invasive technique that enhances tumor management.
- To effectively utilize liquid biopsy, precise isolation of CTCs and their molecular identification through advanced technologies is essential for understanding cancer heterogeneity and improving diagnosis and monitoring.
Article Synopsis
- Mesenchymal stem cell-derived exosomes (MSC-Exos) are gaining attention for their roles in immunomodulation, potentially aiding in the diagnosis and treatment of diseases like cancer and autoimmune disorders.
- These exosomes carry a variety of biological materials, such as proteins and nucleic acids, which can serve as biomarkers and therapeutic options.
- MSC-Exos influence immune responses by interacting with immune cells, leading to better-targeted therapies and diagnostics, highlighting their future promise in personalized medicine and healthcare advancements.
The pathophysiology of several illnesses, including cancer and autoimmune diseasesdepends on human regulatory T cells (Tregs), and abnormalities in these cells may function as triggers for these conditions. Cancer and autoimmune, and gynecological diseases are associated with the differentiation of the proinflammatory T cell subset TH17 and its balance with the production of Treg. Recently, long non-coding RNAs (lncRNAs) have become important regulatory molecules in a wide range of illnesses.
View Article and Find Full Text PDFArticle Synopsis
- - Oral Squamous Cell Carcinoma (OSCC) is the most prevalent head and neck cancer globally, with emerging research highlighting its connection to the oral microbiota, which includes bacteria, fungi, viruses, and archaea.
- - Pathogenic bacteria and certain oral fungi, along with the human papillomavirus, have been particularly associated with the development of OSCC.
- - The exact ways in which the oral microbiota contributes to OSCC are still not fully understood, prompting the need for more research into potential carcinogenic pathways influenced by these microbial communities.
The novel photocatalyst of FeO@SiO/PAEDTC@MIL-101(Fe) was prepared based on the sol-gel method, and its structure and morphology were determined by SEM mapping, TEM, XRD, FTIR, and N adsorption-desorption analyses. The photocatalytic activity of nanocomposite was evaluated in comparison with other particles as well as adsorption and photolysis processes. The effect of operating parameters showed that the complete degradation of penicillin G (PNG) can be provided at a photocatalyst dosage of 0.
View Article and Find Full Text PDFBackground: The adverse health influences of polycyclic aromatic hydrocarbons (PAHs) exposures have been examined in several previous research. However, the evidence on the health influences of PAHs exposure during pregnancy and childhood is scarce, with no study on the infant's liver function. Therefore, in this study, the association of in-utero exposure to particulate matter-bound PAHs (PM-bound PAHs) on the umbilical liver enzymes was investigated.
View Article and Find Full Text PDF