Quantitative frontal and temporal structural MRI studies in personality-disordered offenders and control subjects.

High rates of temporal and frontal lobe dysfunction have been reported in neuropsychological and EEG studies of incarcerated personality-disordered (PD) offenders, but there have been few quantitative structural magnetic resonance imaging (MRI) studies. We investigated whether impulsive-aggressive male PD patients showed evidence of reduced brain volumes in frontal and temporal brain regions on MRI compared with healthy control subjects. All subjects were screened for axis I pathology and brain abnormalities.