IgA-Type Enterovirus Antibodies Are Increased among Adults and Children with Recently Diagnosed Type 1 Diabetes.

Enteroviruses (EV) are among the leading environmental triggers of childhood-onset type 1 diabetes (T1D). Our aim was to determine the prevalence of antibodies against EV and their association with T1D in different age groups ( = 62), including young adults, and to compare these data with results from HLA-matched control participants ( = 62). IgA, IgG, and IgM antibodies against EV were detected.

Enterovirus infections in young infants: are children still protected by maternal antibodies?

Enterovirus infections are frequent in childhood and may be involved in development of several chronic diseases including type 1 diabetes. Maternal antibodies have a protective effect in young infants. It has been proposed that this protection is now vanishing due to decreasing circulation of enteroviruses in Western countries.

Demonstration of high prevalence of SS-A antibodies in a general population: association with HLA-DR and enterovirus antibodies.

Autoantibodies are helpful markers for diagnosing autoimmune diseases and there is a link between HLA-DR3 and the prevalence of SS-A antibodies in clinical groups. We aimed to study this association at the level of general adult population and to verify whether these antibodies are more common in persons with antibodies against enteroviruses as possible associates of Sjögren syndrome. The studied material included sera from 200 persons, randomly selected from a general population sample.